A case of autoimmune hepatitis following administration of the COVID19 vaccine

• Published in: Kanzo Vol. 63; no. 11; pp. 491 - 499
• Main Authors: Yagi, Sen, Tamai, Junichirou, Watanabe, Takao, Yoshida, Makoto, Tokumoto, Yoshio, Abe, Masanori, Murakami, Kazuki, Satou, Makoto, Niida, Kazuki, Miyamoto, Yuuya, Umeoka, Fumi, Murakami, Hidehiro, Okita, Shunji, Miyaoka, Hiroaki, Okada, Takeshi, Hiasa, Youichi
• Format: Journal Article
• Language: English; Japanese
• Published: The Japan Society of Hepatology 01.11.2022
• Subjects: acute liver injury; autoimmune hepatitis; COVID19 vaccine; drug-induced liver injury; lymphocyte stimulation test

A 73-year-old woman developed jaundice 2 days after receiving her second dose of the SARS-CoV-2 vaccine (Pfizer-BioNTech). She had positive antinuclear and antismooth muscle antibodies and an elevated serum immunoglobulin G level. A liver biopsy revealed massive necrosis. Since her drug-induced lymp...