Incidental Diagnosis of Primary Pleural Liposarcoma in a COVID-19-Positive Patient

A few cases of primary liposarcoma of pleura have been reported worldwide. We report a young gentleman who was admitted with what was initially thought as coronavirus disease 2019 (COVID-19)-related pulmonary symptoms. His chest CT showed a large pleural effusion causing a mediastinal shift and comp...

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Published inCurēus (Palo Alto, CA) Vol. 15; no. 7
Main Authors Al Harrasi, Khoula, Al-Kindi, Adil H, Al Lawati, Abdullah, Al Hosni, Fatma, Al Shezawi, Asma
Format Journal Article
LanguageEnglish
Published Palo Alto Cureus Inc 20.07.2023
Cureus
Subjects
Cardiac/Thoracic/Vascular Surgery
Chemotherapy
Coronaviruses
COVID-19
General Surgery
Hemothorax
Hospitals
Liposarcoma
Medical diagnosis
Ostomy
Pleural effusion
Radiation therapy
Surgery
Tumors
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Abstract A few cases of primary liposarcoma of pleura have been reported worldwide. We report a young gentleman who was admitted with what was initially thought as coronavirus disease 2019 (COVID-19)-related pulmonary symptoms. His chest CT showed a large pleural effusion causing a mediastinal shift and compressing vital structures. He did not respond to conservative drainage intervention and subsequently underwent a left thoracotomy for his worsening clinical picture. He was found to have a large left pleural mass that was incompletely resected. Histopathology examination showed low-grade soft tissue sarcoma with lipogenic differentiation suggestive of myxoid liposarcoma. He was subsequently given adjuvant chemotherapy but succumbed and died because of the progression of the disease.
AbstractList A few cases of primary liposarcoma of pleura have been reported worldwide. We report a young gentleman who was admitted with what was initially thought as coronavirus disease 2019 (COVID-19)-related pulmonary symptoms. His chest CT showed a large pleural effusion causing a mediastinal shift and compressing vital structures. He did not respond to conservative drainage intervention and subsequently underwent a left thoracotomy for his worsening clinical picture. He was found to have a large left pleural mass that was incompletely resected. Histopathology examination showed low-grade soft tissue sarcoma with lipogenic differentiation suggestive of myxoid liposarcoma. He was subsequently given adjuvant chemotherapy but succumbed and died because of the progression of the disease.
A few cases of primary liposarcoma of pleura have been reported worldwide. We report a young gentleman who was admitted with what was initially thought as coronavirus disease 2019 (COVID-19)-related pulmonary symptoms. His chest CT showed a large pleural effusion causing a mediastinal shift and compressing vital structures. He did not respond to conservative drainage intervention and subsequently underwent a left thoracotomy for his worsening clinical picture. He was found to have a large left pleural mass that was incompletely resected. Histopathology examination showed low-grade soft tissue sarcoma with lipogenic differentiation suggestive of myxoid liposarcoma. He was subsequently given adjuvant chemotherapy but succumbed and died because of the progression of the disease.
Author Al-Kindi, Adil H
Al Hosni, Fatma
Al Harrasi, Khoula
Al Lawati, Abdullah
Al Shezawi, Asma
AuthorAffiliation 1 General Surgery, Sohar Hospital, Sohar, OMN
4 Radiology, Sohar Hospital, Sohar, OMN
3 College of Medicine and Health Sciences, Sultan Qaboos University, Muscat, OMN
2 Cardiothoracic Surgery, Sultan Qaboos University Hospital, Muscat, OMN
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10.1016/s1010-7940(01)00848-x
10.1016/j.ccm.2012.12.001
10.3978/j.issn.2072-1439.2014.07.30
10.1055/s-2000-6888
10.1510/icvts.2005.108332
10.1016/s0025-6196(12)61792-3
10.1148/radiographics.20.4.g00jl021007
10.1016/s0720-048x(00)00168-6
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Copyright © 2023, Al Harrasi et al. 2023 Al Harrasi et al.
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SubjectTerms Cardiac/Thoracic/Vascular Surgery
Chemotherapy
Coronaviruses
COVID-19
General Surgery
Hemothorax
Hospitals
Liposarcoma
Medical diagnosis
Ostomy
Pleural effusion
Radiation therapy
Surgery
Tumors
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Title Incidental Diagnosis of Primary Pleural Liposarcoma in a COVID-19-Positive Patient
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