Carrageenan Matrix for Sustained Levofloxacin Delivery: Formulation Strategies and Dual Evaluation Approaches

Purpose This study presents the formulation and evaluation of a sustained-release matrix tablet for levofloxacin (LFX) using carrageenan (CRG) as a natural, multifunctional excipient. Methods The complexation between LFX and CRG was optimized through saturation binding studies, demonstrating stable...

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Bibliographic Details
Published inJournal of pharmaceutical innovation Vol. 20; no. 4
Main Authors Abdullah, Samaa, Thiab, Samar, A. Al-Masud, Alaa, Marzoog Al-Sharafa, Meshal, Ardakani, Adel
Format Journal Article
LanguageEnglish
Published New York Springer US 01.08.2025
Subjects
Biochemical Engineering
Biomedical and Life Sciences
Biomedicine
Biotechnology
Industrial and Production Engineering
Pharmacology/Toxicology
Levofloxacin
Complexation
Carrageenan
Sustained-release matrix
absorption
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