Effect of N-Acetylcysteine on Oxidative Stress and Hematological Recovery in Dogs with Babesia Gibsoni Infection

• Published in: Acta parasitologica Vol. 70; no. 5; p. 186
• Main Authors: Mundassery, Asma Idress, Latha, Rathish Ramachandran, Kulangara, Vinodkumar, Mampilli, Pradeep, Chitharalil, Bipin Kuriyedath, Abbdulkhaderkunju, Janus, Meleppat, Deepa Padinjare
• Format: Journal Article
• Language: English
• Published: Cham Springer International Publishing 19.08.2025; Springer Nature B.V
• Subjects: Acetylcysteine; Acetylcysteine - administration & dosage; Acetylcysteine - therapeutic use; Anemia; Animal Systematics/Taxonomy/Biogeography; Animals; Antioxidants; Babesia - drug effects; Babesiosis; Babesiosis - blood; Babesiosis - drug therapy; Babesiosis - parasitology; Bilirubin; Biomedical and Life Sciences; Biomedicine; Clindamycin; Creatinine; Dog Diseases - drug therapy; Dog Diseases - parasitology; Dogs; Doxycycline; Drug Therapy, Combination; Ecology; Female; Hematology; Hemoglobin; Hemolytic anemia; Infections; Inflammation; Male; Medical Microbiology; Metronidazole; Microbiology; Oxidative stress; Oxidative Stress - drug effects; Parameters; Parasitemia; Parasitology; Platelets; Recovery; Renal function; Thrombocytopenia; Oxidative stress; Canine babesiosis; Adjunct therapy; N-acetylcysteine; Babesia gibsoni

Babesia gibsoni infection in dogs causes hemolytic anemia, thrombocytopenia, and systemic inflammation, with many cases progressing to chronic or relapsing forms due to persistent parasitemia and oxidative stress. This study evaluated the clinical, hematobiochemical, and oxidative changes associated...