Studying Metabolic Brain Connectivity Using 2-Deoxy-2-[18F]Fluoro-D-Glucose Dynamic Positron Emission Tomography at the Single-subject Level

• Published in: Journal of visualized experiments no. 215
• Main Authors: Lajtos, Melissa, Raedt, Robrecht, Neyt, Sara, De Herdt, Veerle, Vanhove, Christian
• Format: Journal Article
• Language: English
• Published: United States 24.01.2025
• Subjects: Animals; Brain - diagnostic imaging; Brain - metabolism; Fluorodeoxyglucose F18 - administration & dosage; Fluorodeoxyglucose F18 - chemistry; Fluorodeoxyglucose F18 - pharmacokinetics; Male; Positron-Emission Tomography - methods; Radiopharmaceuticals - pharmacokinetics; Rats

To this day, metabolic brain connectivity is mostly studied on a group level through the acquisition of static positron emission tomography (PET) data of multiple subjects. Our research groups are currently studying changes in metabolic connectivity across multiple time points following an intracere...