Two cases of pigmented nevus of the oral mucosa

A pigmented nevus is defined as a hamartomatous proliferation of nevus cells. It is a very common skin lesion. Pigmented nevi of the oral mucosa are considered a rare lesion and only a few cases have been reported in Japan. We recently encountered 2 cases of pigmented nevus. The first case was in a...

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Published inJapanese Journal of Oral and Maxillofacial Surgery Vol. 42; no. 12; pp. 1215 - 1217
Main Authors SAKOH, Makoto, TAKAHASHI, Tatsuo, CHINO, Megumi, TAKAISHI, Akira, OGIUCHI, Hideki, KANEKO, Hiroyuki, KATAUMI, Hiroaki, FUKADA, Kenji
Format Journal Article
LanguageEnglish
Published Japanese Society of Oral and Maxillofacial Surgeons 1996
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ISSN0021-5163
2186-1579
DOI10.5794/jjoms.42.1215

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Abstract A pigmented nevus is defined as a hamartomatous proliferation of nevus cells. It is a very common skin lesion. Pigmented nevi of the oral mucosa are considered a rare lesion and only a few cases have been reported in Japan. We recently encountered 2 cases of pigmented nevus. The first case was in a 26-year-old man. The nevus was located on the buccal mucosa and measured 4×5mm. The other case was in a 23-year-old woman. She had a nevus on the palatal mucosa for about 15 years. The nevus had grown slowly and measured 40×18×5mm at the time of presentation. She had no symptoms. The nevus was resected in both patients. There has been no recurence in either patient as of 2 year after the operation.
AbstractList A pigmented nevus is defined as a hamartomatous proliferation of nevus cells. It is a very common skin lesion. Pigmented nevi of the oral mucosa are considered a rare lesion and only a few cases have been reported in Japan. We recently encountered 2 cases of pigmented nevus. The first case was in a 26-year-old man. The nevus was located on the buccal mucosa and measured 4×5mm. The other case was in a 23-year-old woman. She had a nevus on the palatal mucosa for about 15 years. The nevus had grown slowly and measured 40×18×5mm at the time of presentation. She had no symptoms. The nevus was resected in both patients. There has been no recurence in either patient as of 2 year after the operation.
Author FUKADA, Kenji
TAKAISHI, Akira
OGIUCHI, Hideki
SAKOH, Makoto
TAKAHASHI, Tatsuo
KATAUMI, Hiroaki
CHINO, Megumi
KANEKO, Hiroyuki
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References 14) Villa, V. G. and Laico, J. E.: Intradermal nevus in the oral cavity evidently developing into a primary melanoma; report of case, J Oral Surg Anes Hopt D Stry 19: 329-333 1961.
7) 高木寿史, 橋本淳二, 他: 口腔内に発生した色素性母斑の免疫組織学的検索. 日口外誌39: 423-427 1993.
13) Clark, W. H. Jr., From, L., et al: The histogenesis and biologic behavior of primary human malignant melanomas of the skin. Cancer Res 29: 705-726 1969.
5) 山崎万里子, 公文義貢: 硬口蓋腫瘍 (母斑) の一症例について. 耳鼻臨床53: 354-358 1960.
2) Seldman, R. E. J., Helwing, E. B., et al: Histological typing of skin tumors, International histological classification of tumors. ed 1, W. H. O., Geneva 1974 66-70.
9) Moore, B. W.: A soluble protein characteristic of the nervous system. Biochem Biophys Res Commun 19: 739-744 1965.
10) 中島孝, 石原和之: IV. S-100蛋白. 皮膚臨床28: 1081-1088 1986.
11) Allen, A. C. and Spitz, S.: Malignant malanoma; A clinicopathological analysis of the criteria for diagnosis and prognosis. Cander 6: 1-45 1953.
3) 石川梧朗, 秋吉正豊: 口腔病理学II. 第3版, 永末書店, 京都, 1971, 1004頁.
12) Allen, A. C. and Spitz, S.: Histogenesis and clinicopathologic correlation of nevi and malignant malanomas. Arch Dermatol Syph 69: 150-171 1954.
6) 高森康次, 海老原務, 他: 色素性母斑の2例と文献的考察. 口科誌40: 469-478 1991.
8) 玉城廣保, 山家誠, 他: 下顎歯肉に発生した色素性母斑の1例 (抄). 口科誌37: 1155 1988.
15) 森嶋隆文, 遠藤幹夫, 他: 色素性母斑上に生じた悪性黒色腫について. 臨皮29: 657-662 1975.
1) 川村太郎: 母斑細胞の期限と母斑症の病理発生 (1). 皮膚臨床19: 255-263 1977.
4) Field, H. J. and Ackerman, A. A.: Nonpigmented Nevus on Labial Mucosa. J Oral Surg. 12: 257-259 1954.
References_xml – reference: 11) Allen, A. C. and Spitz, S.: Malignant malanoma; A clinicopathological analysis of the criteria for diagnosis and prognosis. Cander 6: 1-45 1953.
– reference: 14) Villa, V. G. and Laico, J. E.: Intradermal nevus in the oral cavity evidently developing into a primary melanoma; report of case, J Oral Surg Anes Hopt D Stry 19: 329-333 1961.
– reference: 6) 高森康次, 海老原務, 他: 色素性母斑の2例と文献的考察. 口科誌40: 469-478 1991.
– reference: 13) Clark, W. H. Jr., From, L., et al: The histogenesis and biologic behavior of primary human malignant melanomas of the skin. Cancer Res 29: 705-726 1969.
– reference: 8) 玉城廣保, 山家誠, 他: 下顎歯肉に発生した色素性母斑の1例 (抄). 口科誌37: 1155 1988.
– reference: 15) 森嶋隆文, 遠藤幹夫, 他: 色素性母斑上に生じた悪性黒色腫について. 臨皮29: 657-662 1975.
– reference: 5) 山崎万里子, 公文義貢: 硬口蓋腫瘍 (母斑) の一症例について. 耳鼻臨床53: 354-358 1960.
– reference: 7) 高木寿史, 橋本淳二, 他: 口腔内に発生した色素性母斑の免疫組織学的検索. 日口外誌39: 423-427 1993.
– reference: 1) 川村太郎: 母斑細胞の期限と母斑症の病理発生 (1). 皮膚臨床19: 255-263 1977.
– reference: 2) Seldman, R. E. J., Helwing, E. B., et al: Histological typing of skin tumors, International histological classification of tumors. ed 1, W. H. O., Geneva 1974 66-70.
– reference: 9) Moore, B. W.: A soluble protein characteristic of the nervous system. Biochem Biophys Res Commun 19: 739-744 1965.
– reference: 3) 石川梧朗, 秋吉正豊: 口腔病理学II. 第3版, 永末書店, 京都, 1971, 1004頁.
– reference: 10) 中島孝, 石原和之: IV. S-100蛋白. 皮膚臨床28: 1081-1088 1986.
– reference: 4) Field, H. J. and Ackerman, A. A.: Nonpigmented Nevus on Labial Mucosa. J Oral Surg. 12: 257-259 1954.
– reference: 12) Allen, A. C. and Spitz, S.: Histogenesis and clinicopathologic correlation of nevi and malignant malanomas. Arch Dermatol Syph 69: 150-171 1954.
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SubjectTerms palatine lesion
pigmented nevus
S-100 protein
Title Two cases of pigmented nevus of the oral mucosa
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