Transient hypoxia-ischemia in rats: changes in diffusion-sensitive MR imaging findings, extracellular space, and Na+-K+ -adenosine triphosphatase and cytochrome oxidase activity

• Published in: Radiology Vol. 223; no. 1; p. 65
• Main Authors: Qiao, Min, Malisza, Krisztina L, Del Bigio, Marc R, Tuor, Ursula I
• Format: Journal Article
• Language: English
• Published: United States 01.04.2002
• Subjects: Animals; Diffusion; Electron Transport Complex IV - metabolism; Extracellular Space - enzymology; Female; Hypoxia-Ischemia, Brain - enzymology; Hypoxia-Ischemia, Brain - pathology; Magnetic Resonance Imaging; Pregnancy; Rats; Rats, Wistar; Sodium-Potassium-Exchanging ATPase - metabolism

To investigate the correlation between diffusion-weighted (DW) magnetic resonance (MR) image changes with alterations in extracellular volume and changes in cytochrome oxidase and Na(+)-K(+)-adenosine triphosphatase (ATPase) activity at various times during and after cerebral hypoxia-ischemia in neo...