Correlation of matrix metalloproteinase suppressor genes RECK, VEGF, and CD105 with angiogenesis and biological behavior in esophageal squamous cell carcinoma

• Published in: World journal of gastroenterology : WJG Vol. 13; no. 45; pp. 6076 - 6081
• Main Author: Li, Sheng-Lei
• Format: Journal Article
• Language: English
• Published: United States Department of Pathology, The First Affiliated Hospital Zhengzhou University 07.12.2007; He'nan Key Laboratory of Tumor Pathology,Zhengzhou 450052, He'nan Province, China
• Subjects: Adult; Aged; Antigens, CD - metabolism; Carcinoma, Squamous Cell - blood supply; Carcinoma, Squamous Cell - diagnosis; Carcinoma, Squamous Cell - metabolism; CD105; Early Diagnosis; Endoglin; Esophageal Neoplasms - blood supply; Esophageal Neoplasms - diagnosis; Esophageal Neoplasms - metabolism; Esophagus - pathology; Female; Gene Expression; GPI-Linked Proteins; Humans; Hyperplasia - diagnosis; Hyperplasia - metabolism; Male; Membrane Glycoproteins - metabolism; Middle Aged; Neoplasm Metastasis; Neovascularization, Pathologic - metabolism; Prognosis; Receptors, Cell Surface - metabolism; Vascular Endothelial Growth Factor A - metabolism; 半胱氨酸; 抑制基因; 生物学行为; 食管癌; Immunohistochemistry; Reversion inducing cysteine rich protein with Kazal motifs; Esophageal squamous cell carcinoma; CD105; Microvessel density; Vascular endothelial growth factor

AIM： To explore the expression of reversion inducing cysteine-rich protein with Kazal motifs （RECK）, vascular endothelial growth factor （VEGF） and endoglin （CD105） protein and its correlation with occurrence, development, invasion and metastasis in esophageal squamous cell carcinoma （ESCC）. METHODS：...