Modelling disturbances in early sensory processing in schizophrenia

• Published in: Mitteilungen der Gesellschaft für Angewandte Mathematik und Mechanik Vol. 32; no. 1; pp. 93 - 104
• Main Authors: Popovych, S., Küpper, T., Müller, R., Brockhaus-Dumke, A.
• Format: Journal Article
• Language: English
• Published: Berlin WILEY-VCH Verlag 01.06.2009; WILEY‐VCH Verlag
• Subjects: EEG; phase oscillators; phase reset; schizophrenia; synchronisation

Recent results suggest that disturbances of information processing within the thalamo‐cortical circuit are central in the pathophysiology of schizophrenia. We derive a mathematical model based on phase oscillators to describe the neural activity within the thalamo‐cortical loop and show that the res...