Spectroscopic Investigation on the Interaction of a Cyanine Dye with Serum Albumins

• Published in: Chinese journal of chemistry Vol. 26; no. 2; pp. 397 - 401
• Main Authors: ZHANG, Ya-Zhou, YANG, Qian-Fan, DU, Hong-Yan, TANG, Ya-Lin, XU, Guang-Zhi, YAN, Wen-Peng
• Format: Journal Article
• Language: English
• Published: Weinheim WILEY-VCH Verlag 01.02.2008; WILEY‐VCH Verlag
• Subjects: bovine serum albumin; cyanine dye; fluorescent probe; human serum albumin

The interactions of a cyanine dye with human serum albumin (HSA) and bovine serum albumin (BSA) have been investigated by using absorption and fluorescence spectra. Absorption spectral studies show that binding to the serum albumins leads to a bathochromic shift of the monomer band together with a n...