Revisiting the CXCL13/CXCR5 axis in the tumor microenvironment in the era of single-cell omics: Implications for immunotherapy

• Published in: Cancer letters Vol. 605; p. 217278
• Main Authors: Gu, Xuanyu, Li, Dongyu, Wu, Peng, Zhang, Chaoqi, Cui, Xinyu, Shang, Dexin, Ma, Ruijie, Liu, Jingjing, Sun, Nan, He, Jie
• Format: Journal Article
• Language: English
• Published: Ireland Elsevier B.V 28.11.2024
• Subjects: CXCL13; CXCR5; Immunotherapy; scRNA-seq; Tumor microenvironment; CXCR5; scRNA-seq; Tumor microenvironment; CXCL13; Immunotherapy

As one of the important members of the family of chemokines and their receptors, the CXCL13/CXCR5 axis is involved in follicle formation in normal lymphoid tissues and the establishment of somatic cavity immunity under physiological conditions, as well as being associated with a wide range of infect...