Application of a bespoke monoclonal antibody panel to characterize immune cell populations in cave nectar bats

• Published in: Cell reports (Cambridge) Vol. 43; no. 9; p. 114703
• Main Authors: Chen, Shiwei, Sia, Wan Rong, Tang, Leon J.W., Gamage, Akshamal M., Chan, Wharton O.Y., Zhu, Feng, Chia, Wanni, Kwek, Madeline S.S., Kong, Pui San, Lim, Beng Lee, Foo, Randy, Ng, Wei Lun, Tan, Adrian H.J., He, Shan, Loh, Abigail Y.T., Low, Dolyce H.W., Smith, Gavin J.D., Hong, Lewis Z., Wang, Lin-Fa
• Format: Journal Article
• Language: English
• Published: United States Elsevier Inc 24.09.2024
• Subjects: bat; disease tolerance; immunology; mAb; monoclonal antibody; CP: Immunology; bat; monoclonal antibody; immunology; disease tolerance; mAb

Among their many unique biological features, bats are increasingly recognized as a key reservoir of many emerging viruses that cause massive morbidity and mortality in humans. Bats are capable of harboring many of these deadly viruses without any apparent signs of pathology, in a mechanism known as...