Induction of Petite Colonies in Candida glabrate via Rose Bengal-Mediated Photodynamic Therapy

• Published in: Journal of visualized experiments no. 205
• Main Authors: Yang, Cai-Ying, Hung, Jia-Horung, Wu, Chi-Jung, Wang, Zhao-Xiang, Wang, Shih-Han, Liaw, Hao-Chun, Lin, I-Huang, Yu, Chun-Keung, Wong, Tak-Wah
• Format: Journal Article
• Language: English
• Published: United States 29.03.2024

Facing a 40% mortality rate in candidemia patients, drug-resistant Candida and their petite mutants remain a major treatment challenge. Antimicrobial photodynamic therapy (aPDT) targets multiple fungal structures, unlike antibiotics/antifungals, potentially thwarting resistance. Traditional methods...