Protective role of ferulic acid on carbon tetrachloride-induced hyperlipidemia and histological alterations in experimental rats

• Published in: Journal of basic and clinical physiology and pharmacology Vol. 24; no. 1; pp. 59 - 66
• Main Authors: Marimuthu, Srinivasan, Adluri, Ram Sudheer, Rajagopalan, Rukkumani, Menon, Venugopal Padmanabhan
• Format: Journal Article
• Language: English
• Published: Germany Walter de Gruyter GmbH 2013
• Subjects: Animals; Carbon Tetrachloride - toxicity; Cholesterol - metabolism; Coumaric Acids - pharmacology; Disease Models, Animal; Fatty Acids, Nonesterified - metabolism; Female; Hyperlipidemias - drug therapy; Hypolipidemic Agents - pharmacology; Kidney - drug effects; Kidney - metabolism; Liver - drug effects; Liver - metabolism; Rats; Rats, Wistar; Triglycerides - metabolism

The present study aimed to evaluate the antihyperlipidemic effect of ferulic acid (FA) on carbon tetrachloride (CCl4)-treated rats. Female albino rats of the Wistar strain were used in the present study. The rats were divided into four groups: groups 1 and 4 received physiological saline (3 mL/kg bo...