Synthesis and anti-bacterial activity of some azo compounds

Some azo compounds were prepared by the reaction of 4-amino benzamide with benzoyl chloride forming N-benzoyl-4-amino benzamide, the later was diazotized to give N-benzoyl-4-((substituted phenyl)diazenyl)benzamide (1-6). The compounds were characterized by F.T-IR, 1H-NMR and 13C-NMR. The azo derivat...

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Bibliographic Details
Published inJournal of physics. Conference series Vol. 1294; no. 5; pp. 52038 - 52041
Main Authors Abdul Sattar, Omar D, Shneshil, Mustafa K, Mohammed, Mustafa K, Dheyab, Hiba B, Alwan, Osama K, Hussein, Suaad A, Mahmood, Maha A
Format Journal Article
LanguageEnglish
Published Bristol IOP Publishing 01.09.2019
Subjects
Amide
Anti-bacterial
Azo compounds
Benzamide
Dilution
E coli
NMR
Nuclear magnetic resonance
Physics
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Summary:Some azo compounds were prepared by the reaction of 4-amino benzamide with benzoyl chloride forming N-benzoyl-4-amino benzamide, the later was diazotized to give N-benzoyl-4-((substituted phenyl)diazenyl)benzamide (1-6). The compounds were characterized by F.T-IR, 1H-NMR and 13C-NMR. The azo derivatives (1-6) were tested for their antibacterial activity against (S. aureus, S. epidermidis, E. coli and P. aeruginosa) by using disc diffusion method. The minimum inhibitory concentrations (MICs) of the compounds also calculated by agar streak dilution method. The azo derivatives show moderate activity against the used bacteria.
ISSN:1742-6588
1742-6596
DOI:10.1088/1742-6596/1294/5/052038