Quantification of tissue sodium concentration in the ischemic stroke: A comparison between external and internal references for 23Na MRI

•23Na MRI enables the quantification of tissue sodium concentration (TSC).•TSC quantification is primarily performed based on external reference phantoms.•Internal references have the potential to simplify 23Na MR imaging.•CSF and the vitreous humor as internal references on 50 stroke patients.•Quan...

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Published inJournal of neuroscience methods Vol. 382; p. 109721
Main Authors Adlung, Anne, Licht, Christian, Reichert, Simon, Özdemir, Safa, Mohamed, Sherif A., Samartzi, Melina, Fatar, Marc, Gass, Achim, Prost, Eva Neumaier, Schad, Lothar R.
Format Journal Article
LanguageEnglish
Published Elsevier B.V 01.12.2022
Subjects
23Na MRI
Quantitative MRI
Sodium MRI
Stroke
Tissue sodium concentration
23Na MRI
Stroke
Tissue sodium concentration
Sodium MRI
Quantitative MRI
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Summary:•23Na MRI enables the quantification of tissue sodium concentration (TSC).•TSC quantification is primarily performed based on external reference phantoms.•Internal references have the potential to simplify 23Na MR imaging.•CSF and the vitreous humor as internal references on 50 stroke patients.•Quantification based on the vitreous humor provided most robust results.
Bibliography:ObjectType-Article-1
SourceType-Scholarly Journals-1
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content type line 23
ISSN:0165-0270
1872-678X
DOI:10.1016/j.jneumeth.2022.109721