Patients with Acute Lower Limb Ischemia Continue to Have Significant Morbidity and Mortality
The treatment of acute lower limb ischemia (ALLI) has evolved over the last several decades with the availability of several new treatment modalities. This study was undertaken to evaluate the contemporary presentation and outcomes of ALLI patients. We retrospectively analyzed data from a prospectiv...
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Published in | Annals of vascular surgery Vol. 108; pp. 127 - 140 |
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Main Authors | , , , , , , , |
Format | Journal Article |
Language | English |
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Elsevier Inc
01.11.2024
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Abstract | The treatment of acute lower limb ischemia (ALLI) has evolved over the last several decades with the availability of several new treatment modalities. This study was undertaken to evaluate the contemporary presentation and outcomes of ALLI patients.
We retrospectively analyzed data from a prospectively collected database of all patients who presented to our tertiary referral hospital with acute ischemia of the lower extremity between May 2016 and October 2020. The cause of death was obtained from the Michigan State Death Registry.
During the study period, 233 patients (251 lower limbs) were evaluated for ALLI. Seventy-three percent had thrombotic occlusion, 24% had embolic occlusion, and 3% due to a low flow state. Rutherford classification of ischemia severity was 7%, 49%, 40%, and 4% for Rutherford grade I, IIA, IIB, and III, respectively. Five percent underwent primary amputations, and 6% received medical therapy only. The mean length of stay was 11 ± 9 days. Nineteen percent of patients were readmitted within 30 days of discharge. At 30 days postoperatively, mortality was 9% and limb loss was 19%. On multivariate analysis, 1 or no vessel runoff to the foot postoperatively was associated with higher 30-day limb loss. Patients with no run-off vessels postoperatively had significantly higher 30-day mortality. Cardiovascular complications accounted for most deaths (48%). At 1-year postoperatively, mortality and limb loss reached 17% and 34%, respectively.
Despite advances in treatment modalities and cardiovascular care, patients presenting with ALLI continue to have high mortality, limb loss, and readmission rates at 30 days. |
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AbstractList | The treatment of acute lower limb ischemia (ALLI) has evolved over the last several decades with the availability of several new treatment modalities. This study was undertaken to evaluate the contemporary presentation and outcomes of ALLI patients.
We retrospectively analyzed data from a prospectively collected database of all patients who presented to our tertiary referral hospital with acute ischemia of the lower extremity between May 2016 and October 2020. The cause of death was obtained from the Michigan State Death Registry.
During the study period, 233 patients (251 lower limbs) were evaluated for ALLI. Seventy-three percent had thrombotic occlusion, 24% had embolic occlusion, and 3% due to a low flow state. Rutherford classification of ischemia severity was 7%, 49%, 40%, and 4% for Rutherford grade I, IIA, IIB, and III, respectively. Five percent underwent primary amputations, and 6% received medical therapy only. The mean length of stay was 11 ± 9 days. Nineteen percent of patients were readmitted within 30 days of discharge. At 30 days postoperatively, mortality was 9% and limb loss was 19%. On multivariate analysis, 1 or no vessel runoff to the foot postoperatively was associated with higher 30-day limb loss. Patients with no run-off vessels postoperatively had significantly higher 30-day mortality. Cardiovascular complications accounted for most deaths (48%). At 1-year postoperatively, mortality and limb loss reached 17% and 34%, respectively.
Despite advances in treatment modalities and cardiovascular care, patients presenting with ALLI continue to have high mortality, limb loss, and readmission rates at 30 days. The treatment of acute lower limb ischemia (ALLI) has evolved over the last several decades with the availability of several new treatment modalities. This study was undertaken to evaluate the contemporary presentation and outcomes of ALLI patients.BACKGROUNDThe treatment of acute lower limb ischemia (ALLI) has evolved over the last several decades with the availability of several new treatment modalities. This study was undertaken to evaluate the contemporary presentation and outcomes of ALLI patients.We retrospectively analyzed data from a prospectively collected database of all patients who presented to our tertiary referral hospital with acute ischemia of the lower extremity between May 2016 and October 2020. The cause of death was obtained from the Michigan State Death Registry.METHODSWe retrospectively analyzed data from a prospectively collected database of all patients who presented to our tertiary referral hospital with acute ischemia of the lower extremity between May 2016 and October 2020. The cause of death was obtained from the Michigan State Death Registry.During the study period, 233 patients (251 lower limbs) were evaluated for ALLI. Seventy-three percent had thrombotic occlusion, 24% had embolic occlusion, and 3% due to a low flow state. Rutherford classification of ischemia severity was 7%, 49%, 40%, and 4% for Rutherford grade I, IIA, IIB, and III, respectively. Five percent underwent primary amputations, and 6% received medical therapy only. The mean length of stay was 11 ± 9 days. Nineteen percent of patients were readmitted within 30 days of discharge. At 30 days postoperatively, mortality was 9% and limb loss was 19%. On multivariate analysis, 1 or no vessel runoff to the foot postoperatively was associated with higher 30-day limb loss. Patients with no run-off vessels postoperatively had significantly higher 30-day mortality. Cardiovascular complications accounted for most deaths (48%). At 1-year postoperatively, mortality and limb loss reached 17% and 34%, respectively.RESULTSDuring the study period, 233 patients (251 lower limbs) were evaluated for ALLI. Seventy-three percent had thrombotic occlusion, 24% had embolic occlusion, and 3% due to a low flow state. Rutherford classification of ischemia severity was 7%, 49%, 40%, and 4% for Rutherford grade I, IIA, IIB, and III, respectively. Five percent underwent primary amputations, and 6% received medical therapy only. The mean length of stay was 11 ± 9 days. Nineteen percent of patients were readmitted within 30 days of discharge. At 30 days postoperatively, mortality was 9% and limb loss was 19%. On multivariate analysis, 1 or no vessel runoff to the foot postoperatively was associated with higher 30-day limb loss. Patients with no run-off vessels postoperatively had significantly higher 30-day mortality. Cardiovascular complications accounted for most deaths (48%). At 1-year postoperatively, mortality and limb loss reached 17% and 34%, respectively.Despite advances in treatment modalities and cardiovascular care, patients presenting with ALLI continue to have high mortality, limb loss, and readmission rates at 30 days.CONCLUSIONSDespite advances in treatment modalities and cardiovascular care, patients presenting with ALLI continue to have high mortality, limb loss, and readmission rates at 30 days. |
Author | Rteil, Ali Nypaver, Timothy J. Lee, Alice Weaver, Mitchell Dobesh, Kaitlyn Kabbani, Loay S. Natour, Abdul Kader Shepard, Alexander D. |
Author_xml | – sequence: 1 givenname: Kaitlyn orcidid: 0000-0002-7177-2468 surname: Dobesh fullname: Dobesh, Kaitlyn email: kdobesh1@hfhs.org organization: Division of Vascular Surgery, Henry Ford Hospital, Detroit, MI – sequence: 2 givenname: Abdul Kader surname: Natour fullname: Natour, Abdul Kader organization: Division of Vascular Surgery, Mayo Clinic, Rochester, MN – sequence: 3 givenname: Loay S. surname: Kabbani fullname: Kabbani, Loay S. organization: Division of Vascular Surgery, Henry Ford Hospital, Detroit, MI – sequence: 4 givenname: Ali surname: Rteil fullname: Rteil, Ali organization: Division of Vascular Surgery, Henry Ford Hospital, Detroit, MI – sequence: 5 givenname: Alice surname: Lee fullname: Lee, Alice organization: Division of Vascular Surgery, Henry Ford Hospital, Detroit, MI – sequence: 6 givenname: Timothy J. surname: Nypaver fullname: Nypaver, Timothy J. organization: Division of Vascular Surgery, Henry Ford Hospital, Detroit, MI – sequence: 7 givenname: Mitchell surname: Weaver fullname: Weaver, Mitchell organization: Division of Vascular Surgery, Henry Ford Hospital, Detroit, MI – sequence: 8 givenname: Alexander D. surname: Shepard fullname: Shepard, Alexander D. email: ashepar2@hfhs.org organization: Division of Vascular Surgery, Henry Ford Hospital, Detroit, MI |
BackLink | https://www.ncbi.nlm.nih.gov/pubmed/38848889$$D View this record in MEDLINE/PubMed |
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Cites_doi | 10.1016/S0741-5214(94)70214-4 10.1186/s12959-021-00349-9 10.3389/fcvm.2020.557420 10.1155/2017/2362769 10.1016/S1078-5884(98)80135-4 10.1016/j.jvs.2014.03.244 10.1056/NEJM199804163381603 10.1016/S0002-9610(98)00163-9 10.1161/CIRCINTERVENTIONS.119.008150 10.1016/j.jvs.2019.10.079 10.1016/j.jvs.2013.04.036 10.1016/j.jvs.2018.08.174 10.1016/j.ejvs.2021.10.044 10.1097/00000658-199409000-00003 10.1097/01.sla.0000086663.49670.d1 10.3390/jcm9051501 10.1016/j.avsg.2018.11.025 10.1016/j.jvs.2019.03.081 10.1016/j.jvs.2015.09.055 10.1016/S0741-5214(97)70045-4 10.1007/s00270-001-0095-6 10.1067/mva.2003.176 10.1016/j.jvs.2014.06.109 10.1016/j.jvs.2019.05.031 10.1053/ejvs.1998.0709 10.1016/j.jvs.2019.02.016 10.1016/j.ejvs.2021.01.004 10.1055/s-2006-948765 10.1002/14651858.CD002784.pub3 10.1177/1526602815592849 10.1016/j.avsg.2017.12.025 10.3390/jcm8081215 |
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References | Liang, Zhou, Ye (bib27) 2019; 58 Lopez, Yamashita, Neisen (bib16) 2020; 72 Rutherford, Baker, Ernst (bib9) 1997; 26 Baril, Ghosh, Rosen (bib4) 2014; 60 Hemingway, Emanuels, Aarabi (bib32) 2019; 69 Kulezic, Acosta (bib5) 2022; 63 Lukasiewicz (bib7) 2020; 9 Fogarty, Cranley, Krause (bib10) 1963; 116 Lian, Das, Hu (bib29) 2020; 71 Ouriel, Veith, Sasahara (bib13) 1998; 338 Darwood, Berridge, Kessel (bib35) 2018 Taha, Byrne, Avgerinos (bib33) 2015; 61 (bib12) 1994; 220 Dormandy, Heeck, Vig (bib2) 1999; 12 Nypaver, White, Endean (bib8) 1998; 176 Kolte, Kennedy, Shishehbor (bib36) 2020; 13 Eliason, Wainess, Proctor (bib24) 2003; 238 Baril, Patel, Judelson (bib6) 2013; 58 de Donato, Pasqui, Sponza (bib17) 2021; 61 Ouriel, Shortell, DeWeese (bib14) 1994; 19 Leung, Blitz, Nelson (bib15) 2015; 22 Veenstra, van der Laan, Zeebregts (bib11) 2020; 71 Davis, Albright, Gallagher (bib30) 2018; 51 Acosta, Kuoppala (bib28) 2015; 56 Wang, Kim, Kashyap (bib34) 2016; 63 Conte, Bradbury, Kolh (bib3) 2019; 69 Pemberton, Varty, Nydahl (bib26) 1999; 17 Bérczi, Deutschmann, Schedlbauer (bib22) 2002; 25 Aune, Trippestad (bib25) 1998; 15 Loffroy, Falvo, Galland (bib19) 2020; 7 Olinic, Stanek, Tataru (bib1) 2019; 8 Heller, Lubanda, Varejka (bib18) 2017; 2017 Artzner, Martin, Hefferman (bib21) 2023; 195 Silingardi, Cataldi, Moratto (bib23) 2010; 51 Gong, He, Zhao (bib20) 2021; 19 Morrison (bib37) 2006; 23 Conrad, Shepard, Rubinfeld (bib31) 2003; 37 de Donato (10.1016/j.avsg.2024.03.024_bib17) 2021; 61 Ouriel (10.1016/j.avsg.2024.03.024_bib14) 1994; 19 Gong (10.1016/j.avsg.2024.03.024_bib20) 2021; 19 Silingardi (10.1016/j.avsg.2024.03.024_bib23) 2010; 51 Artzner (10.1016/j.avsg.2024.03.024_bib21) 2023; 195 Darwood (10.1016/j.avsg.2024.03.024_bib35) 2018 Rutherford (10.1016/j.avsg.2024.03.024_bib9) 1997; 26 Eliason (10.1016/j.avsg.2024.03.024_bib24) 2003; 238 Conte (10.1016/j.avsg.2024.03.024_bib3) 2019; 69 Veenstra (10.1016/j.avsg.2024.03.024_bib11) 2020; 71 Aune (10.1016/j.avsg.2024.03.024_bib25) 1998; 15 Dormandy (10.1016/j.avsg.2024.03.024_bib2) 1999; 12 Baril (10.1016/j.avsg.2024.03.024_bib6) 2013; 58 Bérczi (10.1016/j.avsg.2024.03.024_bib22) 2002; 25 Ouriel (10.1016/j.avsg.2024.03.024_bib13) 1998; 338 Olinic (10.1016/j.avsg.2024.03.024_bib1) 2019; 8 Conrad (10.1016/j.avsg.2024.03.024_bib31) 2003; 37 Kolte (10.1016/j.avsg.2024.03.024_bib36) 2020; 13 Nypaver (10.1016/j.avsg.2024.03.024_bib8) 1998; 176 Hemingway (10.1016/j.avsg.2024.03.024_bib32) 2019; 69 Lopez (10.1016/j.avsg.2024.03.024_bib16) 2020; 72 Fogarty (10.1016/j.avsg.2024.03.024_bib10) 1963; 116 Pemberton (10.1016/j.avsg.2024.03.024_bib26) 1999; 17 Lukasiewicz (10.1016/j.avsg.2024.03.024_bib7) 2020; 9 Acosta (10.1016/j.avsg.2024.03.024_bib28) 2015; 56 Lian (10.1016/j.avsg.2024.03.024_bib29) 2020; 71 Heller (10.1016/j.avsg.2024.03.024_bib18) 2017; 2017 Davis (10.1016/j.avsg.2024.03.024_bib30) 2018; 51 Wang (10.1016/j.avsg.2024.03.024_bib34) 2016; 63 (10.1016/j.avsg.2024.03.024_bib12) 1994; 220 Taha (10.1016/j.avsg.2024.03.024_bib33) 2015; 61 Baril (10.1016/j.avsg.2024.03.024_bib4) 2014; 60 Morrison (10.1016/j.avsg.2024.03.024_bib37) 2006; 23 Kulezic (10.1016/j.avsg.2024.03.024_bib5) 2022; 63 Leung (10.1016/j.avsg.2024.03.024_bib15) 2015; 22 Loffroy (10.1016/j.avsg.2024.03.024_bib19) 2020; 7 Liang (10.1016/j.avsg.2024.03.024_bib27) 2019; 58 |
References_xml | – volume: 56 start-page: 317 year: 2015 end-page: 324 ident: bib28 article-title: Update on intra-arterial thrombolysis in patients with lower limb ischemia publication-title: J Cardiovasc Surg contributor: fullname: Kuoppala – volume: 26 start-page: 517 year: 1997 end-page: 538 ident: bib9 article-title: Recommended standards for reports dealing with lower extremity ischemia: revised version publication-title: J Vasc Surg contributor: fullname: Ernst – volume: 220 start-page: 251 year: 1994 end-page: 266 ident: bib12 article-title: Results of a prospective randomized trial evaluating surgery versus thrombolysis for ischemia of the lower extremity. The STILE trial publication-title: Ann Surg – volume: 37 start-page: 1009 year: 2003 end-page: 1016 ident: bib31 article-title: Long-term results of catheter-directed thrombolysis for infrainguinal bypass graft occlusion: the urokinase (UK) era publication-title: J Vasc Surg contributor: fullname: Rubinfeld – volume: 7 year: 2020 ident: bib19 article-title: Percutaneous rotational mechanical atherectomy plus thrombectomy using Rotarex S device in patients with acute and subacute lower limb ischemia: a review of safety, efficacy, and outcomes publication-title: Front Cardiovasc Med contributor: fullname: Galland – volume: 15 start-page: 143 year: 1998 end-page: 146 ident: bib25 article-title: Operative mortality and long-term survival of patients operated on for acute lower extremity ischaemia publication-title: Eur J Vasc Endovasc Surg contributor: fullname: Trippestad – volume: 69 start-page: 3S year: 2019 end-page: 125S ident: bib3 article-title: Global vascular guidelines on the management of chronic limb-threatening ischemia publication-title: J Vasc Surg contributor: fullname: Kolh – volume: 116 start-page: 241 year: 1963 end-page: 244 ident: bib10 article-title: A method for extraction of arterial emboli and thrombi publication-title: Surg Gynecol Obstet contributor: fullname: Krause – volume: 72 start-page: 226 year: 2020 end-page: 232 ident: bib16 article-title: Single-center experience with Indigo aspiration thrombectomy for acute lower limb ischemia publication-title: J Vasc Surg contributor: fullname: Neisen – volume: 338 start-page: 1105 year: 1998 end-page: 1111 ident: bib13 article-title: A comparison of recombinant urokinase with vascular surgery as initial treatment for acute arterial occlusion of the legs. Thrombolysis or Peripheral Arterial Surgery (TOPAS) Investigators publication-title: N Engl J Med contributor: fullname: Sasahara – volume: 176 start-page: 147 year: 1998 end-page: 152 ident: bib8 article-title: Non traumatic lower-extremity acute arterial ischaemia publication-title: Am J Surg contributor: fullname: Endean – volume: 19 start-page: 1021 year: 1994 end-page: 1030 ident: bib14 article-title: A comparison of thrombolytic therapy with operative revascularization in the initial treatment of acute peripheral arterial ischemia publication-title: J Vasc Surg contributor: fullname: DeWeese – volume: 2017 year: 2017 ident: bib18 article-title: Percutaneous mechanical thrombectomy using Rotarex® S device in acute limb ischemia in infrainguinal occlusions publication-title: BioMed Res Int contributor: fullname: Varejka – volume: 195 start-page: 406 year: 2023 end-page: 415 ident: bib21 article-title: Safety and efficacy of rotational thrombectomy for treatment of arterial occlusions of the lower extremities: a large single-center retrospective study publication-title: Röfo contributor: fullname: Hefferman – volume: 13 year: 2020 ident: bib36 article-title: Endovascular versus surgical revascularization for acute limb ischemia: a propensity-score matched analysis publication-title: Circ Cardiovasc Interv contributor: fullname: Shishehbor – volume: 61 start-page: 820 year: 2021 end-page: 828 ident: bib17 article-title: INDIAN trial collaborators. Safety and efficacy of vacuum assisted thrombo-aspiration in patients with acute lower limb ischaemia: the INDIAN trial publication-title: Eur J Vasc Endovasc Surg contributor: fullname: Sponza – volume: 23 start-page: 258 year: 2006 end-page: 269 ident: bib37 article-title: Catheter-directed thrombolysis for acute limb ischemia publication-title: Semin Intervent Radiol contributor: fullname: Morrison – volume: 71 start-page: 654 year: 2020 end-page: 668.e3 ident: bib11 article-title: A systematic review and meta-analysis of endovascular and surgical revascularization techniques in acute limb ischemia publication-title: J Vasc Surg contributor: fullname: Zeebregts – volume: 22 start-page: 546 year: 2015 end-page: 557 ident: bib15 article-title: Rheolytic pharmacomechanical thrombectomy for the management of acute limb ischemia: results from the PEARL Registry publication-title: J Endovasc Ther contributor: fullname: Nelson – volume: 69 start-page: 1174 year: 2019 end-page: 1179 ident: bib32 article-title: Safety of transfer, type of procedure, and factors predictive of limb salvage in a modern series of acute limb ischemia publication-title: J Vasc Surg contributor: fullname: Aarabi – volume: 51 start-page: 543 year: 2010 end-page: 550 ident: bib23 article-title: Mechanical thrombectomy in in-stent restenosis: preliminary experience at the iliac and femoropopliteal arteries with the Rotarex System publication-title: J Cardiovasc Surg contributor: fullname: Moratto – volume: 17 start-page: 72 year: 1999 end-page: 76 ident: bib26 article-title: The surgical management of acute limb ischaemia due to native vessel occlusion publication-title: Eur J Vasc Endovasc Surg contributor: fullname: Nydahl – volume: 58 start-page: 151 year: 2019 end-page: 159 ident: bib27 article-title: Limb salvage after percutaneous mechanical thrombectomy in patients with acute lower limb ischemia: a retrospective analysis from two institutions publication-title: Ann Vasc Surg contributor: fullname: Ye – volume: 25 start-page: 275 year: 2002 end-page: 281 ident: bib22 article-title: Early experience and midterm follow-up results with a new, rotational thrombectomy catheter publication-title: Cardiovasc Intervent Radiol contributor: fullname: Schedlbauer – volume: 51 start-page: 106 year: 2018 end-page: 112 ident: bib30 article-title: Early outcomes following endovascular, open surgical, and hybrid revascularization for lower extremity acute limb ischemia publication-title: Ann Vasc Surg contributor: fullname: Gallagher – volume: 63 start-page: 270 year: 2016 end-page: 278 ident: bib34 article-title: Open surgical or endovascular revascularization for acute limb ischemia publication-title: J Vasc Surg contributor: fullname: Kashyap – volume: 58 start-page: 949 year: 2013 end-page: 956 ident: bib6 article-title: Outcomes of lower extremity bypass performed for acute limb ischemia publication-title: J Vasc Surg contributor: fullname: Judelson – volume: 19 start-page: 96 year: 2021 ident: bib20 article-title: Endovascular revascularization strategies using catheter-based thrombectomy versus conventional catheter-directed thrombolysis for acute limb ischemia publication-title: Thromb J contributor: fullname: Zhao – volume: 9 start-page: 1501 year: 2020 ident: bib7 article-title: Contemporary management of acute lower limb ischemia: determinants of treatment choice publication-title: J Clin Med contributor: fullname: Lukasiewicz – volume: 8 start-page: 1215 year: 2019 ident: bib1 article-title: Acute limb ischemia: an update on diagnosis and management publication-title: J Clin Med contributor: fullname: Tataru – volume: 12 start-page: 148 year: 1999 end-page: 153 ident: bib2 article-title: Acute limb ischemia publication-title: Semin Vasc Surg contributor: fullname: Vig – volume: 60 start-page: 669 year: 2014 end-page: 677.e2 ident: bib4 article-title: Trends in the incidence, treatment, and outcomes of acute lower extremity ischemia in the United States Medicare population publication-title: J Vasc Surg contributor: fullname: Rosen – year: 2018 ident: bib35 article-title: Surgery versus thrombolysis for initial management of acute limb ischaemia publication-title: Cochrane Database Syst Rev contributor: fullname: Kessel – volume: 238 start-page: 382 year: 2003 end-page: 389 ident: bib24 article-title: A national and single institutional experience in the contemporary treatment of acute lower extremity ischemia publication-title: Ann Surg contributor: fullname: Proctor – volume: 61 start-page: 147 year: 2015 end-page: 154 ident: bib33 article-title: Comparative effectiveness of endovascular versus surgical revascularization for acute lower extremity ischemia publication-title: J Vasc Surg contributor: fullname: Avgerinos – volume: 71 start-page: 141 year: 2020 end-page: 148 ident: bib29 article-title: Efficacy of intra-arterial catheter-directed thrombolysis for popliteal and infrapopliteal acute limb ischemia publication-title: J Vasc Surg contributor: fullname: Hu – volume: 63 start-page: 296 year: 2022 end-page: 303 ident: bib5 article-title: Epidemiology and prognostic factors in acute lower limb ischaemia: a population based study publication-title: Eur J Vasc Endovasc Surg contributor: fullname: Acosta – volume: 19 start-page: 1021 year: 1994 ident: 10.1016/j.avsg.2024.03.024_bib14 article-title: A comparison of thrombolytic therapy with operative revascularization in the initial treatment of acute peripheral arterial ischemia publication-title: J Vasc Surg doi: 10.1016/S0741-5214(94)70214-4 contributor: fullname: Ouriel – volume: 19 start-page: 96 year: 2021 ident: 10.1016/j.avsg.2024.03.024_bib20 article-title: Endovascular revascularization strategies using catheter-based thrombectomy versus conventional catheter-directed thrombolysis for acute limb ischemia publication-title: Thromb J doi: 10.1186/s12959-021-00349-9 contributor: fullname: Gong – volume: 7 year: 2020 ident: 10.1016/j.avsg.2024.03.024_bib19 article-title: Percutaneous rotational mechanical atherectomy plus thrombectomy using Rotarex S device in patients with acute and subacute lower limb ischemia: a review of safety, efficacy, and outcomes publication-title: Front Cardiovasc Med doi: 10.3389/fcvm.2020.557420 contributor: fullname: Loffroy – volume: 2017 year: 2017 ident: 10.1016/j.avsg.2024.03.024_bib18 article-title: Percutaneous mechanical thrombectomy using Rotarex® S device in acute limb ischemia in infrainguinal occlusions publication-title: BioMed Res Int doi: 10.1155/2017/2362769 contributor: fullname: Heller – volume: 15 start-page: 143 year: 1998 ident: 10.1016/j.avsg.2024.03.024_bib25 article-title: Operative mortality and long-term survival of patients operated on for acute lower extremity ischaemia publication-title: Eur J Vasc Endovasc Surg doi: 10.1016/S1078-5884(98)80135-4 contributor: fullname: Aune – volume: 60 start-page: 669 year: 2014 ident: 10.1016/j.avsg.2024.03.024_bib4 article-title: Trends in the incidence, treatment, and outcomes of acute lower extremity ischemia in the United States Medicare population publication-title: J Vasc Surg doi: 10.1016/j.jvs.2014.03.244 contributor: fullname: Baril – volume: 338 start-page: 1105 year: 1998 ident: 10.1016/j.avsg.2024.03.024_bib13 article-title: A comparison of recombinant urokinase with vascular surgery as initial treatment for acute arterial occlusion of the legs. Thrombolysis or Peripheral Arterial Surgery (TOPAS) Investigators publication-title: N Engl J Med doi: 10.1056/NEJM199804163381603 contributor: fullname: Ouriel – volume: 176 start-page: 147 year: 1998 ident: 10.1016/j.avsg.2024.03.024_bib8 article-title: Non traumatic lower-extremity acute arterial ischaemia publication-title: Am J Surg doi: 10.1016/S0002-9610(98)00163-9 contributor: fullname: Nypaver – volume: 13 year: 2020 ident: 10.1016/j.avsg.2024.03.024_bib36 article-title: Endovascular versus surgical revascularization for acute limb ischemia: a propensity-score matched analysis publication-title: Circ Cardiovasc Interv doi: 10.1161/CIRCINTERVENTIONS.119.008150 contributor: fullname: Kolte – volume: 72 start-page: 226 year: 2020 ident: 10.1016/j.avsg.2024.03.024_bib16 article-title: Single-center experience with Indigo aspiration thrombectomy for acute lower limb ischemia publication-title: J Vasc Surg doi: 10.1016/j.jvs.2019.10.079 contributor: fullname: Lopez – volume: 195 start-page: 406 year: 2023 ident: 10.1016/j.avsg.2024.03.024_bib21 article-title: Safety and efficacy of rotational thrombectomy for treatment of arterial occlusions of the lower extremities: a large single-center retrospective study publication-title: Röfo contributor: fullname: Artzner – volume: 58 start-page: 949 year: 2013 ident: 10.1016/j.avsg.2024.03.024_bib6 article-title: Outcomes of lower extremity bypass performed for acute limb ischemia publication-title: J Vasc Surg doi: 10.1016/j.jvs.2013.04.036 contributor: fullname: Baril – volume: 116 start-page: 241 year: 1963 ident: 10.1016/j.avsg.2024.03.024_bib10 article-title: A method for extraction of arterial emboli and thrombi publication-title: Surg Gynecol Obstet contributor: fullname: Fogarty – volume: 69 start-page: 1174 year: 2019 ident: 10.1016/j.avsg.2024.03.024_bib32 article-title: Safety of transfer, type of procedure, and factors predictive of limb salvage in a modern series of acute limb ischemia publication-title: J Vasc Surg doi: 10.1016/j.jvs.2018.08.174 contributor: fullname: Hemingway – volume: 63 start-page: 296 year: 2022 ident: 10.1016/j.avsg.2024.03.024_bib5 article-title: Epidemiology and prognostic factors in acute lower limb ischaemia: a population based study publication-title: Eur J Vasc Endovasc Surg doi: 10.1016/j.ejvs.2021.10.044 contributor: fullname: Kulezic – volume: 220 start-page: 251 year: 1994 ident: 10.1016/j.avsg.2024.03.024_bib12 article-title: Results of a prospective randomized trial evaluating surgery versus thrombolysis for ischemia of the lower extremity. The STILE trial publication-title: Ann Surg doi: 10.1097/00000658-199409000-00003 – volume: 238 start-page: 382 year: 2003 ident: 10.1016/j.avsg.2024.03.024_bib24 article-title: A national and single institutional experience in the contemporary treatment of acute lower extremity ischemia publication-title: Ann Surg doi: 10.1097/01.sla.0000086663.49670.d1 contributor: fullname: Eliason – volume: 9 start-page: 1501 year: 2020 ident: 10.1016/j.avsg.2024.03.024_bib7 article-title: Contemporary management of acute lower limb ischemia: determinants of treatment choice publication-title: J Clin Med doi: 10.3390/jcm9051501 contributor: fullname: Lukasiewicz – volume: 51 start-page: 543 year: 2010 ident: 10.1016/j.avsg.2024.03.024_bib23 article-title: Mechanical thrombectomy in in-stent restenosis: preliminary experience at the iliac and femoropopliteal arteries with the Rotarex System publication-title: J Cardiovasc Surg contributor: fullname: Silingardi – volume: 58 start-page: 151 year: 2019 ident: 10.1016/j.avsg.2024.03.024_bib27 article-title: Limb salvage after percutaneous mechanical thrombectomy in patients with acute lower limb ischemia: a retrospective analysis from two institutions publication-title: Ann Vasc Surg doi: 10.1016/j.avsg.2018.11.025 contributor: fullname: Liang – volume: 71 start-page: 141 year: 2020 ident: 10.1016/j.avsg.2024.03.024_bib29 article-title: Efficacy of intra-arterial catheter-directed thrombolysis for popliteal and infrapopliteal acute limb ischemia publication-title: J Vasc Surg doi: 10.1016/j.jvs.2019.03.081 contributor: fullname: Lian – volume: 12 start-page: 148 year: 1999 ident: 10.1016/j.avsg.2024.03.024_bib2 article-title: Acute limb ischemia publication-title: Semin Vasc Surg contributor: fullname: Dormandy – volume: 63 start-page: 270 year: 2016 ident: 10.1016/j.avsg.2024.03.024_bib34 article-title: Open surgical or endovascular revascularization for acute limb ischemia publication-title: J Vasc Surg doi: 10.1016/j.jvs.2015.09.055 contributor: fullname: Wang – volume: 26 start-page: 517 year: 1997 ident: 10.1016/j.avsg.2024.03.024_bib9 article-title: Recommended standards for reports dealing with lower extremity ischemia: revised version publication-title: J Vasc Surg doi: 10.1016/S0741-5214(97)70045-4 contributor: fullname: Rutherford – volume: 25 start-page: 275 year: 2002 ident: 10.1016/j.avsg.2024.03.024_bib22 article-title: Early experience and midterm follow-up results with a new, rotational thrombectomy catheter publication-title: Cardiovasc Intervent Radiol doi: 10.1007/s00270-001-0095-6 contributor: fullname: Bérczi – volume: 37 start-page: 1009 year: 2003 ident: 10.1016/j.avsg.2024.03.024_bib31 article-title: Long-term results of catheter-directed thrombolysis for infrainguinal bypass graft occlusion: the urokinase (UK) era publication-title: J Vasc Surg doi: 10.1067/mva.2003.176 contributor: fullname: Conrad – volume: 61 start-page: 147 year: 2015 ident: 10.1016/j.avsg.2024.03.024_bib33 article-title: Comparative effectiveness of endovascular versus surgical revascularization for acute lower extremity ischemia publication-title: J Vasc Surg doi: 10.1016/j.jvs.2014.06.109 contributor: fullname: Taha – volume: 71 start-page: 654 year: 2020 ident: 10.1016/j.avsg.2024.03.024_bib11 article-title: A systematic review and meta-analysis of endovascular and surgical revascularization techniques in acute limb ischemia publication-title: J Vasc Surg doi: 10.1016/j.jvs.2019.05.031 contributor: fullname: Veenstra – volume: 56 start-page: 317 year: 2015 ident: 10.1016/j.avsg.2024.03.024_bib28 article-title: Update on intra-arterial thrombolysis in patients with lower limb ischemia publication-title: J Cardiovasc Surg contributor: fullname: Acosta – volume: 17 start-page: 72 year: 1999 ident: 10.1016/j.avsg.2024.03.024_bib26 article-title: The surgical management of acute limb ischaemia due to native vessel occlusion publication-title: Eur J Vasc Endovasc Surg doi: 10.1053/ejvs.1998.0709 contributor: fullname: Pemberton – volume: 69 start-page: 3S year: 2019 ident: 10.1016/j.avsg.2024.03.024_bib3 article-title: Global vascular guidelines on the management of chronic limb-threatening ischemia publication-title: J Vasc Surg doi: 10.1016/j.jvs.2019.02.016 contributor: fullname: Conte – volume: 61 start-page: 820 year: 2021 ident: 10.1016/j.avsg.2024.03.024_bib17 article-title: INDIAN trial collaborators. Safety and efficacy of vacuum assisted thrombo-aspiration in patients with acute lower limb ischaemia: the INDIAN trial publication-title: Eur J Vasc Endovasc Surg doi: 10.1016/j.ejvs.2021.01.004 contributor: fullname: de Donato – volume: 23 start-page: 258 year: 2006 ident: 10.1016/j.avsg.2024.03.024_bib37 article-title: Catheter-directed thrombolysis for acute limb ischemia publication-title: Semin Intervent Radiol doi: 10.1055/s-2006-948765 contributor: fullname: Morrison – year: 2018 ident: 10.1016/j.avsg.2024.03.024_bib35 article-title: Surgery versus thrombolysis for initial management of acute limb ischaemia publication-title: Cochrane Database Syst Rev doi: 10.1002/14651858.CD002784.pub3 contributor: fullname: Darwood – volume: 22 start-page: 546 year: 2015 ident: 10.1016/j.avsg.2024.03.024_bib15 article-title: Rheolytic pharmacomechanical thrombectomy for the management of acute limb ischemia: results from the PEARL Registry publication-title: J Endovasc Ther doi: 10.1177/1526602815592849 contributor: fullname: Leung – volume: 51 start-page: 106 year: 2018 ident: 10.1016/j.avsg.2024.03.024_bib30 article-title: Early outcomes following endovascular, open surgical, and hybrid revascularization for lower extremity acute limb ischemia publication-title: Ann Vasc Surg doi: 10.1016/j.avsg.2017.12.025 contributor: fullname: Davis – volume: 8 start-page: 1215 year: 2019 ident: 10.1016/j.avsg.2024.03.024_bib1 article-title: Acute limb ischemia: an update on diagnosis and management publication-title: J Clin Med doi: 10.3390/jcm8081215 contributor: fullname: Olinic |
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Snippet | The treatment of acute lower limb ischemia (ALLI) has evolved over the last several decades with the availability of several new treatment modalities. This... |
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SubjectTerms | Acute Disease Aged Aged, 80 and over Amputation, Surgical Databases, Factual Female Humans Ischemia - diagnosis Ischemia - mortality Ischemia - surgery Ischemia - therapy Length of Stay Limb Salvage Lower Extremity - blood supply Male Michigan - epidemiology Middle Aged Patient Readmission Peripheral Arterial Disease - diagnosis Peripheral Arterial Disease - mortality Peripheral Arterial Disease - therapy Registries Retrospective Studies Risk Assessment Risk Factors Time Factors Treatment Outcome |
Title | Patients with Acute Lower Limb Ischemia Continue to Have Significant Morbidity and Mortality |
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