Suscetibilidade antimicrobiana de Staphylococcus spp. isolados de cães com pioderma superficial

Foram obtidas 154 amostras de lesões cutâneas de cães com pioderma superficial atendidos no Serviço de Dermatologia Veterinária do Hospital Veterinário Universitário (HVU) da Universidade Federal de Santa Maria (UFSM), com o objetivo de determinar a suscetibilidade antimicrobiana de isolados de Stap...

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Published inPesquisa veterinária brasileira Vol. 34; no. 4; pp. 355 - 361
Main Authors Silva, Ana Paula da, Schmidt, Claudete, Vargas, Agueda C. de, Maboni, Grazieli, Rampelotto, Carine, Schwab, Marcelo L., Escobar, Talita P., Amaral, Anne S. do
Format Journal Article
LanguageEnglish
Published 01.04.2014
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Abstract Foram obtidas 154 amostras de lesões cutâneas de cães com pioderma superficial atendidos no Serviço de Dermatologia Veterinária do Hospital Veterinário Universitário (HVU) da Universidade Federal de Santa Maria (UFSM), com o objetivo de determinar a suscetibilidade antimicrobiana de isolados de Staphylococcus spp. e avaliar a presença de multirresistência. Após isolamento e identificação, as cepas foram submetidas ao teste de sensibilidade aos antimicrobianos, cujos resultados evidenciaram menores percentuais de resistência à associação amoxicilina e ácido clavulânico (1,9%), cefadroxil (1,9%), cefalexina (1,9%) e vancomicina (0,6%). Os maiores percentuais de resistência foram frente à amoxicilina (60,4%) e penicilina G (60,4%). A multirresistência foi detectada em 23,4% e a resistência à meticilina em 5,8% das amostras. Pode-se concluir que os isolados de Staphylococcus spp. apresentam elevada suscetibilidade aos antimicrobianos comumente utilizados no tratamento dos piodermas superficiais em cães atendidos no HVU-UFSM, como a cefalexina e a amoxicilina associada ao ácido clavulânico, confirmando a eleição desses fármacos para o tratamento de cães com esta afecção. A suscetibilidade diminuída das cepas frente às fluoroquinolonas, também recomendadas pela literatura para o tratamento de pioderma, permite sugerir que estes fármacos não devem mais ser considerados na seleção empírica. A identificação de Staphylococcus spp. multirresistentes na população canina estudada justifica análises bacteriológicas periódicas e regionais de lesões cutâneas de cães com pioderma superficial, a fim de minimizar a seleção de bactérias resistentes, possíveis falhas terapêuticas e também motiva a antimicrobianoterapia prudente. A total of 154 samples of skin lesions were obtained from dogs with superficial pyoderma that were assisted by the Veterinary Dermatology Service at the University Veterinary Hospital (HVU), Universidade Federal de Santa Maria (UFSM), aiming to determine the antimicrobial susceptibility of Staphylococcus spp. isolates and evaluate the presence of multidrug resistance profile. After bacterial isolation and identification, the strains were tested for antimicrobial susceptibility, and the results showed lower percentages of resistance to the amoxicillin and clavulanic acid association (1.9%), cefadroxil (1.9%), cephalexin (1.9%) and vancomycin (0.6%). The highest percentages were towards amoxicillin (60.4%) and penicillin G (60.4%). The multidrug resistance was detected in 23.4% and the methicillin resistance in 5.8% of the samples. It may be concluded that the Staphylococcus spp. isolates present high susceptibility to key antimicrobials used in the treatment of superficial pyodermas in dogs at the HVU-UFSM, such as cephalexin and the amoxicillin and clavulanic acid association, confirming the preference for these drugs when treating dogs with this disorder. The susceptibility of the strains to fluoroquinolones, also recommended in the literature for the treatment of pyodermas, allows suggesting that such drugs should not be considered in the empirical selection. The identification of multidrug-resistant Staphylococcus spp. in the studied canine population justifies periodic and regional bacteriological tests of skin lesions in dogs with superficial pyoderma, possible therapeutic failures and also motivates wise use of antimicrobial therapy.
AbstractList Foram obtidas 154 amostras de lesões cutâneas de cães com pioderma superficial atendidos no Serviço de Dermatologia Veterinária do Hospital Veterinário Universitário (HVU) da Universidade Federal de Santa Maria (UFSM), com o objetivo de determinar a suscetibilidade antimicrobiana de isolados de Staphylococcus spp. e avaliar a presença de multirresistência. Após isolamento e identificação, as cepas foram submetidas ao teste de sensibilidade aos antimicrobianos, cujos resultados evidenciaram menores percentuais de resistência à associação amoxicilina e ácido clavulânico (1,9%), cefadroxil (1,9%), cefalexina (1,9%) e vancomicina (0,6%). Os maiores percentuais de resistência foram frente à amoxicilina (60,4%) e penicilina G (60,4%). A multirresistência foi detectada em 23,4% e a resistência à meticilina em 5,8% das amostras. Pode-se concluir que os isolados de Staphylococcus spp. apresentam elevada suscetibilidade aos antimicrobianos comumente utilizados no tratamento dos piodermas superficiais em cães atendidos no HVU-UFSM, como a cefalexina e a amoxicilina associada ao ácido clavulânico, confirmando a eleição desses fármacos para o tratamento de cães com esta afecção. A suscetibilidade diminuída das cepas frente às fluoroquinolonas, também recomendadas pela literatura para o tratamento de pioderma, permite sugerir que estes fármacos não devem mais ser considerados na seleção empírica. A identificação de Staphylococcus spp. multirresistentes na população canina estudada justifica análises bacteriológicas periódicas e regionais de lesões cutâneas de cães com pioderma superficial, a fim de minimizar a seleção de bactérias resistentes, possíveis falhas terapêuticas e também motiva a antimicrobianoterapia prudente. A total of 154 samples of skin lesions were obtained from dogs with superficial pyoderma that were assisted by the Veterinary Dermatology Service at the University Veterinary Hospital (HVU), Universidade Federal de Santa Maria (UFSM), aiming to determine the antimicrobial susceptibility of Staphylococcus spp. isolates and evaluate the presence of multidrug resistance profile. After bacterial isolation and identification, the strains were tested for antimicrobial susceptibility, and the results showed lower percentages of resistance to the amoxicillin and clavulanic acid association (1.9%), cefadroxil (1.9%), cephalexin (1.9%) and vancomycin (0.6%). The highest percentages were towards amoxicillin (60.4%) and penicillin G (60.4%). The multidrug resistance was detected in 23.4% and the methicillin resistance in 5.8% of the samples. It may be concluded that the Staphylococcus spp. isolates present high susceptibility to key antimicrobials used in the treatment of superficial pyodermas in dogs at the HVU-UFSM, such as cephalexin and the amoxicillin and clavulanic acid association, confirming the preference for these drugs when treating dogs with this disorder. The susceptibility of the strains to fluoroquinolones, also recommended in the literature for the treatment of pyodermas, allows suggesting that such drugs should not be considered in the empirical selection. The identification of multidrug-resistant Staphylococcus spp. in the studied canine population justifies periodic and regional bacteriological tests of skin lesions in dogs with superficial pyoderma, possible therapeutic failures and also motivates wise use of antimicrobial therapy.
Author Schwab, Marcelo L.
Schmidt, Claudete
Silva, Ana Paula da
Rampelotto, Carine
Vargas, Agueda C. de
Amaral, Anne S. do
Maboni, Grazieli
Escobar, Talita P.
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Cites_doi 10.2460/javma.1994.204.03.334
10.1093/jac/dkr367
10.1093/jac/dkm269
10.1016/j.rvsc.2009.01.011
10.1136/vr.158.16.533
10.1016/j.vetmic.2008.06.002
10.2460/javma.2005.226.904
10.1016/j.cvsm.2005.09.014
10.2460/javma.230.2.221
10.1016/j.rvsc.2010.09.014
10.1111/j.1365-3164.2007.00635.x
10.1111/j.1748-5827.2004.tb00180.x
10.1111/j.1748-5827.1991.tb00960.x
10.1177/104063871102300211
10.1111/j.1748-5827.2011.01165.x
10.1590/S1517-83822009000300011
10.1016/j.vetmic.2010.12.018
10.1016/j.vetmic.2011.12.028
10.1111/j.1439-0450.2004.00816.x
10.1111/j.1748-5827.2008.00585.x
10.1093/ajcp/45.4_ts.493
10.1111/j.1365-3164.2011.00995.x
10.1590/S0100-736X2009000200013
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References Pianta C. (ref32) 2006; 5
Souza T.M. (ref35) 2009; 29
Bond R. (ref2) 2012; 56
Cox H.U. (ref6) 2006
Mason I.S. (ref25) 1991; 32
Hill P.B. (ref14) 1994; 204
May E.R. (ref26) 2006; 36
Guardabassi L. (ref13) 2008
Ihrke J.P. (ref19) 2005
Hnilica K.A. (ref16) 2004; 26
Pedersen K. (ref30) 2007; 60
Duijkeren E. (ref8) 2011; 66
Ganiere J.P. (ref10) 2005; 52
Hnilica K.A. (ref17) 2011
Youn J. (ref40) 2011; 23
Spinosa H.S. (ref36) 2002
Ghidini F. (ref11) 2011; 34
Hill P.B. (ref15) 2006; 158
Nienhoff U. (ref27) 2011; 150
Penna B. (ref31) 2009; 40
Duquette R.A. (ref9) 2004; 45
Jones R.D. (ref21) 2007; 230
Lima L.F.A. (ref22) 2012; 3
Lucia M. (ref24) 2011; 91
(ref5) 2006
Devriese L.A. (ref7) 2009; 133
Proietti P.C. (ref33) 2012; 157
Bauer A.W. (ref1) 1966; 45
Toma S. (ref37) 2008; 49
Gross T.L. (ref12) 2005
Scott D.W. (ref34) 2001
Vanni M. (ref38) 2009; 87
Ihrke J.P. (ref20) 2006
Cavalcanti S.N. (ref4) 2005; 58
Carter G.R. (ref3) 1988
Loeffler A. (ref23) 2007; 18
White S.D. (ref39) 2005; 6
Patel A. (ref29) 2010
Horvath C. (ref18) 2007; 12
Onuma K. (ref28) 2011; 23
References_xml – volume: 204
  start-page: 334
  year: 1994
  ident: ref14
  article-title: Canine pyoderma
  publication-title: J. Am. Vet. Med. Assoc.
  doi: 10.2460/javma.1994.204.03.334
  contributor:
    fullname: Hill P.B.
– year: 2005
  ident: ref12
  contributor:
    fullname: Gross T.L.
– volume: 12
  start-page: 55
  year: 2007
  ident: ref18
  article-title: Management of canine pyoderma
  publication-title: UK Vet.
  contributor:
    fullname: Horvath C.
– volume: 66
  start-page: 2705
  year: 2011
  ident: ref8
  article-title: Review on methicillin-resistant Staphylococcus pseudintermedius
  publication-title: J. Antimicrob. Chemother.
  doi: 10.1093/jac/dkr367
  contributor:
    fullname: Duijkeren E.
– year: 2006
  ident: ref5
– volume: 60
  start-page: 775
  year: 2007
  ident: ref30
  article-title: Occurrence of antimicrobial resistance in bacteria from diagnostic samples from dogs
  publication-title: J. Antimicrob. Chemother.
  doi: 10.1093/jac/dkm269
  contributor:
    fullname: Pedersen K.
– volume: 87
  start-page: 192
  year: 2009
  ident: ref38
  article-title: Antimicrobial susceptibility of Staphylococcus intermedius and Staphylococcus schleiferi isolated from dogs
  publication-title: Res. Vet. Sci.
  doi: 10.1016/j.rvsc.2009.01.011
  contributor:
    fullname: Vanni M.
– volume: 158
  start-page: 533
  year: 2006
  ident: ref15
  article-title: Survey of the prevalence, diagnosis and treatment of dermatological conditions in small animals in general practice
  publication-title: Vet. Rec.
  doi: 10.1136/vr.158.16.533
  contributor:
    fullname: Hill P.B.
– year: 2005
  ident: ref19
  contributor:
    fullname: Ihrke J.P.
– volume: 133
  start-page: 206
  year: 2009
  ident: ref7
  article-title: Staphylococcus pseudintermedius versus Staphylococcus intermedius
  publication-title: Vet. Microbiol.
  doi: 10.1016/j.vetmic.2008.06.002
  contributor:
    fullname: Devriese L.A.
– start-page: 161
  year: 2010
  ident: ref29
  contributor:
    fullname: Patel A.
– volume: 6
  start-page: 904
  year: 2005
  ident: ref39
  article-title: Evaluation of aerobic bacteriologic culture of epidermal collarette specimens in dogs with superficial pyoderma
  publication-title: J. Am. Vet. Medic. Assoc.
  doi: 10.2460/javma.2005.226.904
  contributor:
    fullname: White S.D.
– year: 2002
  ident: ref36
  contributor:
    fullname: Spinosa H.S.
– volume: 58
  start-page: 60
  year: 2005
  ident: ref4
  article-title: Identificação e perfil de sensibilidade bacteriana de Staphylococcus spp isolados da pele de cães sadios e com piodermite
  publication-title: Clin. Vet.
  contributor:
    fullname: Cavalcanti S.N.
– volume: 36
  start-page: 185
  year: 2006
  ident: ref26
  article-title: Bacterial skin diseases: current thoughts on pathogenesis and management
  publication-title: Vet. Clin. North Am., Small Anim. Pract.
  doi: 10.1016/j.cvsm.2005.09.014
  contributor:
    fullname: May E.R.
– volume: 230
  start-page: 221
  year: 2007
  ident: ref21
  article-title: Prevalence of oxacilin-and multidrug-resistant staphylococci in clinical samples from dogs: 1772 samples (2001-2005)
  publication-title: J. Am. Vet. Med. Assoc.
  doi: 10.2460/javma.230.2.221
  contributor:
    fullname: Jones R.D.
– start-page: 316
  volume-title: Staphylococcal infections
  year: 2006
  ident: ref6
  contributor:
    fullname: Cox H.U.
– volume: 3
  start-page: 181
  year: 2012
  ident: ref22
  article-title: Antimicrobial resistance in staplylococci isolated from canine pyoderma
  publication-title: Comunicata Scientiae
  contributor:
    fullname: Lima L.F.A.
– volume: 91
  start-page: 346
  year: 2011
  ident: ref24
  article-title: Prevalence of canine methicilin resistant Staphylococcus pseudintermedius in a veterinary diagnostic laboratory in Italy
  publication-title: Res. Vet. Sci.
  doi: 10.1016/j.rvsc.2010.09.014
  contributor:
    fullname: Lucia M.
– year: 2011
  ident: ref17
  contributor:
    fullname: Hnilica K.A.
– volume: 18
  start-page: 412
  year: 2007
  ident: ref23
  article-title: First report of multiresistant, mecA-positive Staphylococcus intermedius in Europe: 12 cases from a veterinary dermatology referral clinic in Germany
  publication-title: Vet. Dermatol.
  doi: 10.1111/j.1365-3164.2007.00635.x
  contributor:
    fullname: Loeffler A.
– volume: 34
  start-page: 403
  year: 2011
  ident: ref11
  article-title: Antibiotic sensitivity of bacterial isolates from cases of canine dermatitis
  publication-title: New Microbiol.
  contributor:
    fullname: Ghidini F.
– volume: 45
  start-page: 591
  year: 2004
  ident: ref9
  article-title: Methicillin-resistant Staphylococcus aureus in dogs and cats: an emerging problem?
  publication-title: J. Small Anim. Pract.
  doi: 10.1111/j.1748-5827.2004.tb00180.x
  contributor:
    fullname: Duquette R.A.
– volume: 32
  start-page: 381
  year: 1991
  ident: ref25
  article-title: Canine pyoderma
  publication-title: J. Small Anim.Pract.
  doi: 10.1111/j.1748-5827.1991.tb00960.x
  contributor:
    fullname: Mason I.S.
– volume: 23
  start-page: 268
  year: 2011
  ident: ref40
  article-title: Prevalence and antimicrogram of Staphylococcus intermedius group isolates from veterinary staff, companion animals, and the environment in veterinary hospitals in Korea
  publication-title: J. Vet. Diagn. Invest.
  doi: 10.1177/104063871102300211
  contributor:
    fullname: Youn J.
– volume: 56
  start-page: 147
  year: 2012
  ident: ref2
  article-title: What's happened to Staphylococcus intermedius?: Taxonomic revision and emergence of multi-drug resistence
  publication-title: J. Small Anim. Pract.
  doi: 10.1111/j.1748-5827.2011.01165.x
  contributor:
    fullname: Bond R.
– volume: 40
  start-page: 490
  year: 2009
  ident: ref31
  article-title: In vitro antimicrobial susceptibility of Staphylococci isolated from canine pyoderma in Rio de Janeiro, Brazil
  publication-title: Braz. J. Microbiol.
  doi: 10.1590/S1517-83822009000300011
  contributor:
    fullname: Penna B.
– year: 1988
  ident: ref3
  contributor:
    fullname: Carter G.R.
– year: 2001
  ident: ref34
  contributor:
    fullname: Scott D.W.
– volume: 150
  start-page: 191
  year: 2011
  ident: ref27
  article-title: Methicillin-resistant Staphylococcus pseudintermedius among dogs admitted to a small animal hospital
  publication-title: Vet. Microbiol.
  doi: 10.1016/j.vetmic.2010.12.018
  contributor:
    fullname: Nienhoff U.
– volume: 157
  start-page: 376
  year: 2012
  ident: ref33
  article-title: Insertion sequence IS256 in canine pyoderma isolates of Staphylococcus pseudintermedius associated with antibiotic resistance
  publication-title: Vet. Microbiol.
  doi: 10.1016/j.vetmic.2011.12.028
  contributor:
    fullname: Proietti P.C.
– volume: 52
  start-page: 25
  year: 2005
  ident: ref10
  article-title: Antimicrobial drug susceptibility of Staphylococcus intermedius clinical isolates from canine pyoderma
  publication-title: J. Vet. Med.
  doi: 10.1111/j.1439-0450.2004.00816.x
  contributor:
    fullname: Ganiere J.P.
– volume: 26
  start-page: 560
  year: 2004
  ident: ref16
  article-title: Staphylococcal pyoderma: an emerging problem
  publication-title: Compend. Contin. Educ. Pract. Vet.
  contributor:
    fullname: Hnilica K.A.
– volume: 49
  start-page: 384
  year: 2008
  ident: ref37
  article-title: Efficacy and tolerability of once-daily cephalexin in canine superficial pyoderma: an open control study
  publication-title: J. Small Anim. Pract.
  doi: 10.1111/j.1748-5827.2008.00585.x
  contributor:
    fullname: Toma S.
– volume: 45
  start-page: 493
  year: 1966
  ident: ref1
  article-title: Antibiotic susceptibility testing by a standardized single disk method
  publication-title: Am. J. Clin. Pathol.
  doi: 10.1093/ajcp/45.4_ts.493
  contributor:
    fullname: Bauer A.W.
– year: 2008
  ident: ref13
  contributor:
    fullname: Guardabassi L.
– volume: 23
  start-page: 17
  year: 2011
  ident: ref28
  article-title: Antimicrobial resistance of Staphylococcus pseudintermedius isolates from healthy dogs and dogs affected with pyoderma in Japan
  publication-title: Vet. Dermatol.
  doi: 10.1111/j.1365-3164.2011.00995.x
  contributor:
    fullname: Onuma K.
– start-page: 807
  volume-title: Integumentary infections
  year: 2006
  ident: ref20
  contributor:
    fullname: Ihrke J.P.
– volume: 29
  start-page: 157
  year: 2009
  ident: ref35
  article-title: Prevalência das dermatopatias não-tumorais em cães do município de Santa Maria, Rio Grande do Sul (2005-2008)
  publication-title: Pesq. Vet. Bras.
  doi: 10.1590/S0100-736X2009000200013
  contributor:
    fullname: Souza T.M.
– volume: 5
  start-page: 60
  year: 2006
  ident: ref32
  article-title: Pioderma estafilococócico canino: identificação das espécies e sensibilidade aos antimicrobianos
  publication-title: Revta Ciênc. Agrovet.
  contributor:
    fullname: Pianta C.
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Snippet Foram obtidas 154 amostras de lesões cutâneas de cães com pioderma superficial atendidos no Serviço de Dermatologia Veterinária do Hospital Veterinário...
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StartPage 355
Title Suscetibilidade antimicrobiana de Staphylococcus spp. isolados de cães com pioderma superficial
Volume 34
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