Jatrophenediol, a pseudoguaiane sesquiterpenoid from Jatropha dioica rhizomes

• Published in: Tetrahedron letters Vol. 104; pp. 154040 - 154042
• Main Authors: Bautista, Elihú, Lozano-Gamboa, Sarahí, Fragoso-Serrano, Mabel, Rivera-Chávez, José, Salazar-Olivo, Luis A.
• Format: Journal Article
• Language: English
• Published: OXFORD Elsevier Ltd 17.08.2022; Elsevier
• Subjects: Chemistry; Chemistry, Organic; Euphorbiaceae; Jatropha species; MDR modulation; Physical Sciences; Science & Technology; Sesquiterpenoids; Structural elucidation; MDR modulation; Structural elucidation; Euphorbiaceae; Jatropha species; Sesquiterpenoids; SYSTEM; DITERPENOIDS; MODULATORS; MULTIDRUG-RESISTANCE; DERIVATIVES; DISCOVERY

[Display omitted] •A novel sesquiterpenoid was identified in Jatropha dioica roots.•Its structure was determined by HRMS and NMR.•The cytotoxic and MDR modulatory capability of the isolates was assayed. Jatrophenediol (1), a new pseudoguaiane sesquiterpenoid was isolated from the roots of Jatropha d...