Cu(II) complexes of flavonoids in solution: Impact of the Cu(II) ion on the antioxidant and DNA-intercalating properties

• Published in: Journal of molecular liquids Vol. 359; p. 119230
• Main Authors: Šimunková, Miriama, Biela, Monika, Štekláč, Marek, Hlinčík, Andrej, Klein, Erik, Malček, Michal
• Format: Journal Article
• Language: English
• Published: Elsevier B.V 01.08.2022
• Subjects: Antioxidant; Copper; DFT; DNA intercalation; Flavonoid; Molecular Docking; DFT; Antioxidant; Copper; DNA intercalation; Flavonoid; Molecular Docking

[Display omitted] •Complexes of Cu(II) with flavonoids are studied in two solvents: DMSO and methanol.•Formation of complexes is monitored by UV-Vis spectroscopy and DFT calculations.•Kaempferol, luteolin and fisetin complexes show enhanced radical scavenging effect.•Molecular docking study indicate...