Network-based modelling reveals cell-type enriched patterns of non-coding RNA regulation during human skeletal muscle remodelling

• Published in: NAR molecular medicine Vol. 1; no. 4; p. ugae016
• Main Authors: Mcleod, Jonathan C, Lim, Changhyun, Stokes, Tanner, Sharif, Jalil-Ahmad, Zeynalli, Vagif, Wiens, Lucas, D’Souza, Alysha C, Colenso-Semple, Lauren, McKendry, James, Morton, Robert W, Mitchell, Cameron J, Oikawa, Sara Y, Wahlestedt, Claes, Chapple, J Paul, McGlory, Chris, Timmons, James A, Phillips, Stuart M
• Format: Journal Article
• Language: English
• Published: England Oxford University Press 01.10.2024

A majority of human genes produce non-protein-coding RNA (ncRNA), and some have roles in development and disease. Neither ncRNA nor human skeletal muscle is ideally studied using short-read sequencing, so we used a customized RNA pipeline and network modelling to study cell-type specific ncRNA respo...