Phenibut, a GABAB Agonist, Detected in a Fatality
Abstract Phenibut, a GABAB agonist structurally similar to baclofen, is not approved for medical use in the USA but is available through internet suppliers for recreational use. Calls to poison control centers for phenibut have increased over the last 5 years, and there are many case reports of seve...
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Published in | Journal of analytical toxicology Vol. 46; no. 2; pp. e73 - e77 |
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Main Authors | , |
Format | Journal Article |
Language | English |
Published |
US
Oxford University Press
14.09.2021
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Subjects | |
Online Access | Get full text |
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Summary: | Abstract
Phenibut, a GABAB agonist structurally similar to baclofen, is not approved for medical use in the USA but is available through internet suppliers for recreational use. Calls to poison control centers for phenibut have increased over the last 5 years, and there are many case reports of severe acute intoxications and withdrawals requiring hospitalization. This case report describes the autopsy and toxicology findings of a 26-year-old male found dead at home with phenibut containers on the scene. Autopsy findings and routine toxicology testing were generally unremarkable. Scene findings prompted the validation of a qualitative liquid chromatography--tandem mass spectrometry method that confirmed the presence of phenibut in blood and urine. |
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ISSN: | 0146-4760 1945-2403 |
DOI: | 10.1093/jat/bkab099 |