Neural expression and regulation of NSSR1 proteins

• Published in: Neuroreport Vol. 14; no. 14; p. 1847
• Main Authors: Liu, Lei, Lin, Jun-Ji, Chen, Xianhua, Liu, Xuan, Xu, Ping
• Format: Journal Article
• Language: English
• Published: England 06.10.2003
• Subjects: Animals; Blotting, Western; Brain - cytology; Brain Chemistry; Carrier Proteins - genetics; Carrier Proteins - metabolism; Cell Cycle Proteins; Cell Differentiation - physiology; Cells, Cultured; Cercopithecus aethiops; Fetus; Gene Expression; Humans; Immunohistochemistry; Male; Mice; Neoplasm Proteins - genetics; Neoplasm Proteins - metabolism; Neurons - metabolism; Repressor Proteins - genetics; Repressor Proteins - metabolism; Reverse Transcriptase Polymerase Chain Reaction - methods; RNA, Messenger - biosynthesis; RNA-Binding Proteins - genetics; RNA-Binding Proteins - metabolism; Serine-Arginine Splicing Factors; Stem Cells - metabolism; Testis - metabolism; Transfection

Neural salient serine-/arginine-rich protein 1 (NSSR1) is a newly identified SR protein that regulates pre-mRNA splicing. In the present study, we demonstrated the neural specialization of NSSR1 protein expression in humans and mice. Strong immunoreactive signals to NSSR1 were observed in mouse cere...