T- and B-lymphocytes subpopulations in the early and advanced rheumatoid arthritis

• Published in: Sovremennai͡a︡ revmatologii͡a Vol. 15; no. 2; pp. 17 - 22
• Main Authors: Martynova, A. V., Popkova, T. V., Aleksankin, A. P., Gridneva, G. I., Gerasimova, E. V., Gorbunova, Yu. N., Semashko, A. S., Lila, A. M.
• Format: Journal Article
• Language: English; Russian
• Published: IMA-PRESS LLC 23.04.2021
• Subjects: cd19+ b-cells; double negative b-cells; flow cytofluorometry; immunogram; memory b-cells; methotrexate; naive b-cells; rheumatoid arthritis

Objective : to evaluate changes in T- and B-lymphocyte subpopulations at different stages of rheumatoid arthritis (RA). Patients and methods . The study included 53 patients with a definite RA diagnosis according to the 2010 ACR/EULAR criteria (mean age 54.2 [47; 62] years). Group 1 included 27 pati...