Identification of the murine H-2Db and human HLA-A0201 MHC class I-restricted HPV6 E7-specific cytotoxic T lymphocyte epitopes

• Published in: Cancer Immunology, Immunotherapy Vol. 65; no. 3; pp. 261 - 271
• Main Authors: Peng, Shiwen, Mattox, Austin, Best, Simon R., Barbu, Anca M., Burns, James A., Akpeng, Belinda, Jeang, Jessica, Yang, Benjamin, Ishida, Eiichi, Hung, Chien-Fu, Wu, Tzyy-Choou, Pai, Sara I.
• Format: Journal Article
• Language: English
• Published: Berlin/Heidelberg Springer Berlin Heidelberg 01.03.2016
• Subjects: Cancer Research; Immunology; Medicine; Medicine & Public Health; Oncology; Original Article; MHC class I; Human papillomavirus; Vaccine; T cell epitope; Recurrent respiratory papillomatosis; Immunotherapy

Recurrent respiratory papillomatosis is caused by human papillomavirus (HPV) infection, most commonly types 6 (HPV-6) and 11 (HPV-11). Due to failed host immune responses, HPV is unable to be cleared from the host, resulting in recurrent growth of HPV-related lesions that can obstruct the lumen of t...