Secondary immunodeficiency (immune paralysis) following spinal cord injury

• Published in: Neuroforum Vol. 1; no. 3; pp. 43 - 51
• Main Authors: Brommer, B., Kopp, M.A., Laginha, I., Schwab, J.M.
• Format: Journal Article
• Language: English
• Published: Heidelberg Spektrum Akademischer Verlag 01.09.2010; De Gruyter
• Subjects: Biomedical and Life Sciences; Biomedicine; Life Sciences; Neurobiology; Neurochemistry; Neurology; Neurosciences; Review Article; Infection; Zentralnervensystem; Immunosuppression; Immunsystem; Immunsuppression; Central nervous system; Spinal cord injuries; Rückenmarkverletzungen; Immune system; Infektion

Infections are a leading cause of morbidity and mortality in patients with acute spinal cord injury (SCI). It has recently become clear that SCI might increase susceptibility to infection by central nervous system (CNS)-specific mechanisms: CNS injury induces a disruption of the normally well-balanc...