Margin Status and Recurrence in Surgically Treated Patients With HPV+ Oropharyngeal Cancer

• Published in: The Laryngoscope Vol. 135; no. 8; p. 2777
• Main Authors: Ausburn, Madeleine, Pyne, Justin M, Day, Andrew T, Hajnas, Natalia, Moon, Dominic, Myers, Larry Leonard, Sher, David Jonathan, Truelson, John M, Tillman, Brittny, Sumer, Baran
• Format: Journal Article
• Language: English
• Published: United States 01.08.2025
• Subjects: Adult; Aged; Aged, 80 and over; Carcinoma, Squamous Cell - mortality; Carcinoma, Squamous Cell - surgery; Carcinoma, Squamous Cell - virology; Female; Follow-Up Studies; Humans; Male; Margins of Excision; Middle Aged; Neoplasm Recurrence, Local - epidemiology; Oropharyngeal Neoplasms - mortality; Oropharyngeal Neoplasms - pathology; Oropharyngeal Neoplasms - surgery; Oropharyngeal Neoplasms - virology; Papillomaviridae; Papillomavirus Infections - complications; Progression-Free Survival; Retrospective Studies; Robotic Surgical Procedures - methods; resection margins; survival outcomes; HPV+ oropharyngeal cancer; transoral robotic surgery; oropharyngeal squamous cell carcinoma

The optimal margins for surgically treated human papilloma virus (HPV)-related oropharyngeal squamous cell carcinoma (OPSCC) remain undefined. We evaluated the impact of surgical margins on progression-free survival (PFS) in patients with HPV+ OPSCC treated with primary transoral robotic surgery (TO...