Classical analgesic drugs modulate nociceptive-like escape behavior in Drosophila melanogaster larvae

• Published in: Research results in pharmacology (English ed.) Vol. 8; no. 4; pp. 185 - 196
• Main Authors: Santos-Silva, Thamyris, Lopes, Caio Fábio Baeta, Gumarães, Jennifer Diniz Soares, Valer, Felipe Berti, Kuhn, Gustavo Campos Silva, Romero, Thiago Roberto Lima, Naves, Lígia Araújo, Duarte, Igor Dimitri Gama
• Format: Journal Article
• Language: English
• Published: Belgorod National Research University 22.12.2022

Introduction: Nociceptive stimulus triggers escape responses in Drosophila melanogaster larvae, characterized by 360° rolling behavior along its own body axis. Therefore, it is possible to study analgesic drugs based on this stereo­typical nociceptive-like escape behavior. Here, we aimed to develop...