Balancing interactions in proline-based receptors for chiral recognition of l-/d-DOPA

• Published in: Organic & biomolecular chemistry Vol. 18; no. 24; pp. 4590 - 4598
• Main Authors: Guo, Lin-E, Tang, Yu-Xin, Zhang, Shu-Ying, Hong, Yuan, Yan, Xiao-Sheng, Li, Zhao, Jiang, Yun-Bao
• Format: Journal Article
• Language: English
• Published: England Royal Society of Chemistry 24.06.2020
• Subjects: Aldehydes; Aqueous solutions; Balancing; Benzaldehyde; Binding; Chemical bonds; Dihydroxyphenylalanine; Fluorine; Proline; Receptors; Recognition; Residues

Proline based receptors (1-14) attached with phenylboronic acid and benzaldehyde binding groups at the N-/C- or C-/N-termini of the proline residue were created for chiral recognition of l-/d-DOPA, in an attempt to examine if balancing the two binding events would influence the recognition. By chang...