Cloning and sequencing of a rearranged Vλ gene from a Burkitt's tymphoma cell line expressing kappa light chains

• Published in: Nucleic acids research Vol. 13; no. 13; pp. 4921 - 4934
• Main Authors: Sun, Lee-Hwei K., Croce, Carlo M., Showe, Louise C.
• Format: Journal Article
• Language: English
• Published: Oxford University Press 11.07.1985

We have cloned and sequenced a rearranged Vλ gene from a Burkitt's lymphoma cell line PA682(PB). This cell line has two rearranged K loci and has been shown to be expressing K light chains (1). This Vλ gene has been identified as a member of the Vλ subgroup III gene family based on the homology...