Lupenone Isolated from Diospyros melanoxylon Bark Non-competitively Inhibits alpha-amylase Activity

• Published in: Biology, medicine, & natural product chemistry (Online) Vol. 12; no. 1; pp. 171 - 176
• Main Authors: Durgam, Mohan Krishna, Vemuri, Praveen Kumar, Bodiga, Vijaya Lakshmi, Bodiga, Sreedhar
• Format: Journal Article
• Language: English
• Published: State Islamic University Sunan Kalijaga 24.01.2023
• Subjects: diospyros melanoxylon; ebenaceae; non-competitive inhibition; pancreatic amylase; triterpenoid ketone

Diabetes mellitus is a chronic disease that poses a serious global health problem, due to its associated effects on obesity and aging. Therapeutic strategies for targeting diabetes include the downregulation and/or inhibition of enzymes such as a-amylase and a-glucosidase, hydrolyzing the dietary ca...