Relatively Increased Number of Liver Foxp3~＋ Regulatory T Cells against Hepatic Lesions in Murine Lupus

• Published in: Journal of Huazhong University of Science and Technology. Medical sciences Vol. 31; no. 4; pp. 476 - 481
• Main Author: 余立凯 黄安斌 王玮炜 杜戎 沈凌汛 侯晓华
• Format: Journal Article
• Language: English
• Published: Heidelberg Huazhong University of Science and Technology 01.08.2011
• Subjects: Medicine; Medicine & Public Health; 小鼠; 程序性细胞死亡; 系统性红斑狼疮; 肝脏病变; 自身免疫性疾病; 调节性T细胞; 逆转录聚合酶链反应; 酶联免疫吸附试验; Foxp3; lupus; hepatic lesion; BXSB mice

Systemic lupus erythematosus（SLE） is a multiple organ autoimmune disorder,including the liver,but the possible reason in impairment in the liver is still unclear.Our present study assessed alterations of transcription factor Foxp3＋ regulatory T cells（Tregs） and several other immune molecules [progra...