A Robust, Safe, and Scalable Magnetic Nanoparticle Workflow for RNA Extraction of Pathogens from Clinical and Wastewater Samples (Global Challenges 4/2021)

A critical bottleneck in COVID‐19 diagnosis and surveillance is the shortage of kits for RNA extraction. In article number 2000068, Mo Li and co‐workers develop a DIY, open‐source, safe, and fast method for magnetic‐nanoparticle‐aided viral RNA isolation from contagious samples (MAVRICS). MAVRICS ri...

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Published inGlobal challenges Vol. 5; no. 4
Main Authors Ramos‐Mandujano, Gerardo, Salunke, Rahul, Mfarrej, Sara, Rachmadi, Andri Taruna, Hala, Sharif, Xu, Jinna, Alofi, Fadwa S., Khogeer, Asim, Hashem, Anwar M., Almontashiri, Naif A. M., Alsomali, Afrah, Shinde, Digambar B., Hamdan, Samir, Hong, Pei‐Ying, Pain, Arnab, Li, Mo
Format Journal Article
LanguageEnglish
Published Hoboken John Wiley and Sons Inc 01.04.2021
Subjects
Cover Picture
influenza
magnetic nanoparticles
nucleic acid purification
SARS‐CoV‐2
wastewater surveillance
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Abstract A critical bottleneck in COVID‐19 diagnosis and surveillance is the shortage of kits for RNA extraction. In article number 2000068, Mo Li and co‐workers develop a DIY, open‐source, safe, and fast method for magnetic‐nanoparticle‐aided viral RNA isolation from contagious samples (MAVRICS). MAVRICS rivals commercial kits in performance and could become an enabling technology for community testing and wastewater monitoring in the current and future pandemics.
AbstractList A critical bottleneck in COVID‐19 diagnosis and surveillance is the shortage of kits for RNA extraction. In article number 2000068, Mo Li and co‐workers develop a DIY, open‐source, safe, and fast method for magnetic‐nanoparticle‐aided viral RNA isolation from contagious samples (MAVRICS). MAVRICS rivals commercial kits in performance and could become an enabling technology for community testing and wastewater monitoring in the current and future pandemics.
A critical bottleneck in COVID‐19 diagnosis and surveillance is the shortage of kits for RNA extraction. In article number 2000068 , Mo Li and co‐workers develop a DIY, open‐source, safe, and fast method for magnetic‐nanoparticle‐aided viral RNA isolation from contagious samples (MAVRICS). MAVRICS rivals commercial kits in performance and could become an enabling technology for community testing and wastewater monitoring in the current and future pandemics.
Author Alsomali, Afrah
Pain, Arnab
Hamdan, Samir
Alofi, Fadwa S.
Almontashiri, Naif A. M.
Salunke, Rahul
Hala, Sharif
Shinde, Digambar B.
Hong, Pei‐Ying
Rachmadi, Andri Taruna
Mfarrej, Sara
Hashem, Anwar M.
Xu, Jinna
Ramos‐Mandujano, Gerardo
Khogeer, Asim
Li, Mo
AuthorAffiliation 1 Biological and Environmental Sciences and Engineering Division (BESE) King Abdullah University of Science and Technology (KAUST) Thuwal 23955‐6900 Kingdom of Saudi Arabia
4 Plan and Research Department General Directorate of Health Affairs Makkah Region Ministry of Health Mecca 11176 Saudi Arabia
2 King Abdullah International Medical Research Centre King Saud University for Health Sciences Ministry of National Guard Health Affairs Jeddah 21859 Saudi Arabia
10 Division of Physical Science and Engineering King Abdullah University of Science and Technology (KAUST) Thuwal 23955‐6900 Kingdom of Saudi Arabia
3 Infectious Diseases Department King Fahad Hospital Almadinah Almunwarah 11525 Saudi Arabia
5 Vaccines and Immunotherapy Unit King Fahd Medical Research Center King Abdulaziz University Jeddah 21859 Saudi Arabia
9 Infectious Diseases Department King Abdullah Medical Complex Jeddah 24246 Saudi Arabia
8 Center for Genetics and Inherited Diseases Taibah University Almadinah Almunwarah 71491 Sau
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Snippet A critical bottleneck in COVID‐19 diagnosis and surveillance is the shortage of kits for RNA extraction. In article number 2000068, Mo Li and co‐workers...
A critical bottleneck in COVID‐19 diagnosis and surveillance is the shortage of kits for RNA extraction. In article number 2000068 , Mo Li and co‐workers...
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SubjectTerms Cover Picture
influenza
magnetic nanoparticles
nucleic acid purification
SARS‐CoV‐2
wastewater surveillance
Title A Robust, Safe, and Scalable Magnetic Nanoparticle Workflow for RNA Extraction of Pathogens from Clinical and Wastewater Samples (Global Challenges 4/2021)
URI https://onlinelibrary.wiley.com/doi/abs/10.1002%2Fgch2.202170041
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Volume 5
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