Effects of d-chiro-inositol in lean women with the polycystic ovary syndrome

• Published in: Endocrine practice Vol. 8; no. 6; pp. 417 - 423
• Main Authors: Iuorno, Maria J, Jakubowicz, Daniela J, Baillargeon, Jean-Patrice, Dillon, Pamela, Gunn, Ronald D, Allan, Geoffrey, Nestler, John E
• Format: Journal Article
• Language: English
• Published: United States Elsevier Limited 01.11.2002
• Subjects: Adolescent; Adult; Blood Glucose - analysis; Blood Pressure; Body Mass Index; Double-Blind Method; Female; Glucose Tolerance Test; Humans; Inositol Phosphates - therapeutic use; Insulin - blood; Insulin Antagonists - therapeutic use; Placebos; Polycystic Ovary Syndrome - drug therapy; Polycystic Ovary Syndrome - physiopathology; Polysaccharides - therapeutic use; Testosterone - blood; Triglycerides - blood

To determine whether the administration of D-chiro-inositol, a putative insulin-sensitizing drug, would affect the concentration of circulating insulin, the levels of serum androgens, and the frequency of ovulation in lean women with the polycystic ovary syndrome. In 20 lean women (body mass index,...