IRF1 transcriptionally activates ALOX15B to enhance ferroptosis sensitivity in triple-negative breast cancer - Peng, Wei; Xie, Yi; Duan, Bofeng; Qian, Fuyong; Fan, Zhifeng; Zheng, Wei (Biochimica et biophysica acta. General subjects, 2025)
Keywords: 15-lipoxygenase; Arachidonate 12-Lipoxygenase - genetics; Arachidonate 12-Lipoxygenase - metabolism; Arachidonate 15-Lipoxygenase - genetics; Arachidonate 15-Lipoxygenase - metabolism; Breast cancer; Cell Line, Tumor; Female; Ferroptosis; Ferroptosis - genetics; Gene Expression Regulation, Neoplastic; Humans; Interferon regulatory factor; Interferon Regulatory Factor-1 - genetics; Interferon Regulatory Factor-1 - metabolism; Reactive Oxygen Species - metabolism; Transcriptional Activation; Triple Negative Breast Neoplasms - genetics; Triple Negative Breast Neoplasms - metabolism; Triple Negative Breast Neoplasms - pathology; Ferroptosis; Breast cancer; 15-lipoxygenase; Interferon regulatory factor