Structural Characterization of Chemical Compounds Based on Their Fragmentation Rules in Sophorae Fructus by UPLC-QTOF-MS/MS

• Published in: Pharmaceutical fronts Vol. 4; no. 3; pp. e162 - e178
• Main Authors: He, Zi-Hui, Liu, Mo, Ren, Jun-Xuan, Ouyang, Dan-Wei
• Format: Journal Article
• Language: English
• Published: Rüdigerstraße 14, 70469 Stuttgart, Germany Georg Thieme Verlag KG 01.09.2022
• Subjects: flavonoid glycosides; fragmentation; Original Article; saponins; sophorae fructus; uplc-q-tof-ms/ms; UPLC-Q-TOF-MS/MS; fragmentation; flavonoid glycosides; saponins

Abstract This study aims to identify the chemical components in Sophorae Fructus , and explore the mass spectrometric cleavage rules using the UPLC-Q-TOF-MS/MS method. The main characteristic fragments of the compounds were analyzed by electrospray ionization (ESI) ion source under positive and nega...