P.55 Dietary Nitrate Prevents Progression of Carotid Subclinical Atherosclerosis Through BP-Independent Mechanisms in Patients with or at Risk of Type 2 Diabetes Mellitus: Results from the Double-Blind, Randomized-Controlled, Factorial Vasera Trial

• Published in: Artery research Vol. 26; no. Suppl 1; p. S77
• Main Authors: Morselli, Franca, Faconti, Luca, Mills, Charlotte E, Morant, Steve, Chowienczyk, Philip J, Cruickshank, J Kennedy, Webb, Andrew J, Cavarape, Alessandro
• Format: Journal Article
• Language: English
• Published: Dordrecht Springer Netherlands 01.12.2020; Springer Nature B.V; BMC
• Subjects: Atherosclerosis; Conference Abstract; Diabetes; intima-media thickness; Nitrate; Nitrates; intima-media thickness; Nitrate

Background Epidemiological and animal studies suggest the potential of dietary nitrate (NO 3 − ) to inhibit atherogenesis. Spironolactone may improve arterial stiffness. We tested if 6 months’ intervention with dietary nitrate and spironolactone could affect carotid subclinical atherosclerosis and s...