Clinical trials in cervical intraepithelial neoplasia: balancing the need for efficacy data with patient safety

• Published in: Journal of lower genital tract disease Vol. 6; no. 4; p. 206
• Main Authors: Silverman, Michael H, Hedley, Mary Lynne, Petry, K Ulrich, Weber, Jeffrey S
• Format: Journal Article
• Language: English
• Published: United States 01.10.2002

OBJECTIVE.: Trial designs for novel nonsurgical, nonablative therapies for cervical intraepithelial neoplasia grades 2 and 3 (CIN 2,3) must ensure patient safety while providing sufficient time to show clinical effects. We propose an observation period based on literature and current practice. MATER...