Differential expression of CD45R0 on natural killer (NK) cells in patients with an NK lymphocytosis

• Published in: Immunology and cell biology Vol. 72; no. 6; p. 500
• Main Authors: Warren, H S, Kinnear, B F, Skipsey, L J, Pembrey, R G
• Format: Journal Article
• Language: English
• Published: United States 01.12.1994
• Subjects: Adult; Cell Division; Cells, Cultured; Female; Flow Cytometry; Humans; Immunophenotyping; In Vitro Techniques; Killer Cells, Natural - immunology; Leukocyte Common Antigens - metabolism; Lymphocytosis - immunology; Lymphocytosis - pathology; Male; Middle Aged

NK cells from three donors with a NK (CD3- CD56+ CD16+) lymphocytosis of unknown aetiology showed differential expression of CD45R0, an isoform of CD45 not expressed by NK cells from normal donors unless stimulated to proliferate in vitro. For donor FC, 60% of NK cells expressed CD45R0 over a 16 mon...