Interstitial fibrosis is associated with left atrial remodeling and adverse clinical outcomes in selected low-risk patients with hypertrophic cardiomyopathy

• Published in: International journal of cardiology Vol. 408; p. 132135
• Main Authors: Tondi, Lara, Pica, Silvia, Crimi, Gabriele, Disabato, Giandomenico, Figliozzi, Stefano, Camporeale, Antonia, Bernardini, Andrea, Tassetti, Luigi, Milani, Valentina, Piepoli, Massimo Francesco, Lombardi, Massimo
• Format: Journal Article
• Language: English
• Published: Netherlands Elsevier B.V 01.08.2024
• Subjects: Adult; Aged; Atrial Function, Left - physiology; Atrial Remodeling - physiology; Cardiomyopathy, Hypertrophic - diagnostic imaging; Cardiomyopathy, Hypertrophic - physiopathology; Extracellular volume; Female; Fibrosis; Follow-Up Studies; Humans; Hypertrophic cardiomyopathy; Left atrium; Magnetic Resonance Imaging, Cine - methods; Male; Middle Aged; Outcomes; Risk Factors; Strain; CMR-FT; AF; r-ECV; LV; Left atrium; LGE; Outcomes; Strain; HCM; LA; Fibrosis; Hypertrophic cardiomyopathy; Extracellular volume; HF

Cardiovascular magnetic resonance (CMR) extracellular volume (ECV) allows non-invasive detection of myocardial interstitial fibrosis, which may be related to diastolic dysfunction and left atrial (LA) remodeling in hypertrophic cardiomyopathy (HCM). While the prognostic role of LGE is well-establish...