A comparative study of bioenergetic metabolism on mammary epithelial cells from humans and Göttingen Minipigs

• Published in: Biochimica et biophysica acta. General subjects Vol. 1868; no. 12; p. 130728
• Main Authors: Algieri, Cristina, Bernardini, Chiara, La Mantia, Debora, Trombetti, Fabiana, Forni, Monica, Nesci, Salvatore
• Format: Journal Article
• Language: English
• Published: Netherlands Elsevier B.V 01.12.2024
• Subjects: Adenosine Triphosphate - metabolism; Animals; ATP; Cell metabolism; Cells, Cultured; Energy Metabolism; Energy production; Epithelial Cells - metabolism; Female; Glycolysis; Göttingen Minipigs mammary epithelial cells; Humans; Humans mammary epithelial cells; Mammary Glands, Animal - cytology; Mammary Glands, Animal - metabolism; Mammary Glands, Human - cytology; Mammary Glands, Human - metabolism; Oxidative Phosphorylation; Swine; Swine, Miniature; Cell metabolism; Humans mammary epithelial cells; Göttingen Minipigs mammary epithelial cells; Energy production; ATP

Mammary epithelial cells (MECs) of humans (h) and Göttingen Minipigs (mp) were analyzed to compare their ability to perform ATP production by oxidative phosphorylation and glycolysis. The ATP production under basal and stressor situations highlights the same metabolic potential of both primary cell...