A Randomized, Double-Blind, Controlled Trial to Assess the Effects of Lactoferrin at Two Doses vs. Active Control on Immunological and Safety Parameters in Healthy Adults

• Published in: International journal of toxicology p. 10915818241293723
• Main Authors: Peterson, Ross D, Guarneiri, Liana L, Adams, Caryn G, Wilcox, Meredith L, Clark, Anthony J, Rudemiller, Nathan P, Maki, Kevin C, Malinczak, Carrie-Anne
• Format: Journal Article
• Language: English
• Published: United States 28.10.2024
• Subjects: bioactive nutrition; food ingredient safety; human lactoferrin; dietary supplements; ingredient risk assessment; alloimmunization; immunogenicity; tolerance

Recombinant human lactoferrin (rhLF) is of commercial interest for immune support as a food ingredient. The objective was to evaluate the immunogenicity/alloimmunization potential of Helaina rhLF (effera™) from over a 28-day period compared to bovine LF (bLF). Study 1 was a randomized, double-blind,...