In-line optical monitoring of oxygen saturation and hematocrit for cardiopulmonary bypass: Adjustment-free and bloodless calibration

Abstract Background and objective: This article describes a new sensor for monitoring oxygen saturation (sO Materials and methods: The optical sensor presented here uses near-infrared spatially resolved reflectance spectroscopy. The primary calibration model for a master sensor is derived from the m...

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Published inPhotonics & lasers in medicine Vol. 4; no. 2; pp. 187 - 192
Main Authors Netz, Uwe J., Friebel, Moritz, Helfmann, Jürgen
Format Journal Article
LanguageEnglish
Published Berlin De Gruyter 01.05.2015
Walter de Gruyter GmbH
Subjects
calibration standard
calibration transfer
heart lung machine
Herzlungenmaschine
Kalibrierstandard
Kalibrierübertragung
optical phantom
optisches Phantom
ortsaufgelöste Rückstreuspektroskopie
spatially resolved reflectance spectroscopy
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Abstract Abstract Background and objective: This article describes a new sensor for monitoring oxygen saturation (sO Materials and methods: The optical sensor presented here uses near-infrared spatially resolved reflectance spectroscopy. The primary calibration model for a master sensor is derived from the measurement of circulating human blood from a number of different patients with references taken from standard laboratory analysis of blood parameters. Transfer of the calibration model from the master sensor to new sensors is performed by measurement of an optical standard made of artificial material with defined and controlled optical properties. Results: The predicted values of sO Conclusion: A new sensor with high degree of accuracy for sO
AbstractList Background and objective: This article describes a new sensor for monitoring oxygen saturation (sO[2]) and hematocrit (Hct) of blood during cardiopulmonary bypass. The sensor is calibrated without blood and does not need to be adjusted by laboratory blood parameter analysis when in operation. Materials and methods: The optical sensor presented here uses near-infrared spatially resolved reflectance spectroscopy. The primary calibration model for a master sensor is derived from the measurement of circulating human blood from a number of different patients with references taken from standard laboratory analysis of blood parameters. Transfer of the calibration model from the master sensor to new sensors is performed by measurement of an optical standard made of artificial material with defined and controlled optical properties. Results: The predicted values of sO[2] and Hct exhibit an accuracy of 1.2% for sO[2] and 1.1% for Hct compared to the reference values. The optical standard yields optical signals similar to the measurement of blood. After calibration transfer, the mean accuracy of the measurement of 10 sensors is 1.3% for sO[2] and 1.2% for Hct. Conclusion: A new sensor with high degree of accuracy for sO[2] and Hct compared to commercially available sensor systems is presented. The calibration transfer using optical standards gives a comparable degree of accuracy. The method could be adapted for use with existing sensors. No animal blood needs to be used in calibration process anymore.
Abstract Background and objective: This article describes a new sensor for monitoring oxygen saturation (sO Materials and methods: The optical sensor presented here uses near-infrared spatially resolved reflectance spectroscopy. The primary calibration model for a master sensor is derived from the measurement of circulating human blood from a number of different patients with references taken from standard laboratory analysis of blood parameters. Transfer of the calibration model from the master sensor to new sensors is performed by measurement of an optical standard made of artificial material with defined and controlled optical properties. Results: The predicted values of sO Conclusion: A new sensor with high degree of accuracy for sO
Author Friebel, Moritz
Netz, Uwe J.
Helfmann, Jürgen
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Cites_doi 067009
10.1016/S0003-4975(02)04697-0
10.1117/1.429919
10.1016/j.mla.2007.09.011
10.1007/s003400050833
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Snippet Abstract Background and objective: This article describes a new sensor for monitoring oxygen saturation (sO Materials and methods: The optical sensor presented...
Background and objective: This article describes a new sensor for monitoring oxygen saturation (sO[2]) and hematocrit (Hct) of blood during cardiopulmonary...
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StartPage 187
SubjectTerms calibration standard
calibration transfer
heart lung machine
Herzlungenmaschine
Kalibrierstandard
Kalibrierübertragung
optical phantom
optisches Phantom
ortsaufgelöste Rückstreuspektroskopie
spatially resolved reflectance spectroscopy
Title In-line optical monitoring of oxygen saturation and hematocrit for cardiopulmonary bypass: Adjustment-free and bloodless calibration
URI http://www.degruyter.com/doi/10.1515/plm-2014-0053
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