Extramedullary myeloid sarcoma mimicking tuberculosis of spine: A case report and literature review

A definitive diagnosis of spinal tuberculosis (TB) remains challenging. The "gold standard" is to obtain histopathological confirmation of the lesion. This analysis highlights how to avoid missing the diagnosis of an extramedullary myeloid sarcoma (EMS) versus TB. A 25-year-old male presen...

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Published inSurgical neurology international Vol. 12; p. 178
Main Authors Patgaonkar, Prasad, Goyal, Vaibhav, Marathe, Nandan
Format Journal Article
LanguageEnglish
Published United States Scientific Scholar 19.04.2021
Subjects
Case Report
Spine
Myeloid sarcoma
Tuberculosis
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Abstract A definitive diagnosis of spinal tuberculosis (TB) remains challenging. The "gold standard" is to obtain histopathological confirmation of the lesion. This analysis highlights how to avoid missing the diagnosis of an extramedullary myeloid sarcoma (EMS) versus TB. A 25-year-old male presented with paraparesis. Although this was first attributed to TB spondylodiscitis, a PET-CT and reevaluation of the biopsy specimen both confirmed the diagnosis of an EMS. Nontubercular spinal disease should be suspected when a patient deteriorates despite the institution of antitubercular therapy for a reasonable duration. Further, microbiological and/or pathological confirmation is warranted to direct appropriate treatment and differentiate spinal TB from other entities as, in this case, an EMS.
AbstractList A definitive diagnosis of spinal tuberculosis (TB) remains challenging. The "gold standard" is to obtain histopathological confirmation of the lesion. This analysis highlights how to avoid missing the diagnosis of an extramedullary myeloid sarcoma (EMS) versus TB. A 25-year-old male presented with paraparesis. Although this was first attributed to TB spondylodiscitis, a PET-CT and reevaluation of the biopsy specimen both confirmed the diagnosis of an EMS. Nontubercular spinal disease should be suspected when a patient deteriorates despite the institution of antitubercular therapy for a reasonable duration. Further, microbiological and/or pathological confirmation is warranted to direct appropriate treatment and differentiate spinal TB from other entities as, in this case, an EMS.
ArticleNumber 178
Author Goyal, Vaibhav
Patgaonkar, Prasad
Marathe, Nandan
AuthorAffiliation 2 Department of Spine Services, Indian Spinal Injuries Centre, New Delhi, India
1 Department of Spine Surgery, Indore Spine Centre, Indore, Madhya Pradesh, India
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10.1002/1097-0142(20001225)90:6<364::AID-CNCR7>3.0.CO;2-1
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Keywords Spine
Myeloid sarcoma
Tuberculosis
Language English
License Copyright: © 2021 Surgical Neurology International.
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Title Extramedullary myeloid sarcoma mimicking tuberculosis of spine: A case report and literature review
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