Effects of genetic variants of ST8SIA2 and NCAM1 genes on seasonal mood changes and circadian preference in the general population

• Published in: Chronobiology international Vol. 35; no. 3; pp. 405 - 415
• Main Authors: Yang, So Yung, Baek, Ji Hyun, Cho, Youngah, Cho, Eun-Young, Choi, Yujin, Kim, Yongkang, Park, Taesung, Hong, Kyung Sue
• Format: Journal Article
• Language: English
• Published: England 04.03.2018
• Subjects: Adult; Affect; CD56 Antigen - genetics; Circadian Rhythm - genetics; Female; Genetic Variation; Genotype; Healthy Volunteers; Humans; Male; Middle Aged; Phenotype; Polymorphism, Single Nucleotide; Seasons; Sialyltransferases - genetics; Young Adult; plasticity; NCAM1; single nucleotide polymorphism; seasonality; ST8SIA2; circadian rhythm

ST8SIA2 and NCAM1 are functionally related genes forming polysialic acid (PSA) - neural cell adhesion molecule (NCAM) complex in suprachiasmatic nucleus (SCN), the regulating site of circadian biological rhythm. In this study, the relationship of ST8SIA2 and NCAM1 with circadian and seasonal rhythms...