Self-calibrated SERS-LFIA biosensor based on AgNF for in-site and rapid detection of protein kinase biomarker PEAK1

• Published in: Biosensors & bioelectronics Vol. 288; p. 117784
• Main Authors: Wang, Yanling, Gao, Yuan, Ge, Xue, Zhuang, Xiwei, Liu, Jianlei, Zhou, Shaoxiong, Li, Mengnan, Zeng, Chijia, Cui, Feiyun, Zhou, Qin
• Format: Journal Article
• Language: English
• Published: England Elsevier B.V 15.11.2025
• Subjects: AgNF; Biomarkers, Tumor - blood; Biosensing Techniques - methods; Biosensor; Humans; Immunoassay - methods; Kinases biomarker; Limit of Detection; Metal Nanoparticles - chemistry; POCT; Pseudopodium-enriched atypical kinase 1 (PEAK1); SERS-LFIA; Silver - chemistry; Spectrum Analysis, Raman - methods; Kinases biomarker; AgNF; Pseudopodium-enriched atypical kinase 1 (PEAK1); SERS-LFIA; POCT; Biosensor

Dysregulation of pseudopodium-enriched atypical kinase 1 (PEAK1) has been implicated in cancer progression and metastasis, highlighting its significance as a biomarker for disease diagnosis and prognosis. The accurate and sensitive detection of PEAK1 is crucial for understanding cellular signaling p...