4565 Sex-Specific Differences in the Genomic Landscape of Pediatric and Adult Glioblastoma

• Published in: Journal of clinical and translational science Vol. 4; no. s1; pp. 112 - 113
• Main Authors: Ivanov, Nikolay A., Dahmane, Nadia, Greenfield, Jeffrey P., Mason, Christopher E.
• Format: Journal Article
• Language: English
• Published: Cambridge Cambridge University Press 01.06.2020
• Subjects: CpG islands; DNA probes; Gene expression; Glioblastoma; Glioma; Pediatrics; Population studies; Precision Medicine; Sex chromosomes; Sexes; Shores; Single-nucleotide polymorphism

OBJECTIVES/GOALS: It has been previously shown that pediatric high-grade glioma (pHGG) survival is different between sexes. We set out to find out whether there are sex-specific differences in the genomic landscapes of pHGG that may underlie this sex disparity. METHODS/STUDY POPULATION: We downloade...