Pulmonary Tuberculosis with Elevated CEA and Positive PET-CT

• Published in: Clinical laboratory (Heidelberg) Vol. 69; no. 4
• Main Authors: Ren, Hong Q, Zhao, Qian, Yang, Wen, Jiang, Jiao, Fu, Ai S, Ge, Yan L
• Format: Journal Article
• Language: English
• Published: Germany 01.04.2023
• Subjects: Fluorodeoxyglucose F18; Humans; Lung Neoplasms - diagnostic imaging; Lung Neoplasms - pathology; Positron Emission Tomography Computed Tomography - methods; Solitary Pulmonary Nodule - diagnosis; Solitary Pulmonary Nodule - pathology; Tuberculosis, Pulmonary - diagnostic imaging
• ISSN: 1433-6510
• DOI: 10.7754/Clin.Lab.2022.220716

Pulmonary tuberculosis presenting as solitary pulmonary nodules in imaging is sometimes difficult to differentiate from lung cancer and is more likely to be misdiagnosed when accompanied by elevated CEA and positive PET-CT findings. By reporting a case of misdiagnosed lung cancer, which was confirmed to be pulmonary tuberculosis by lung biopsy, a joint literature analysis was performed to raise clinicians' awareness of isolated nodules in the lung. With a series of ancillary tests, we initially considered the nodule to be malignant, and the lung biopsy pathology eventually confirmed pulmonary tuberculosis. When chest imaging suggests the presence of malignant features in solitary pulmonary nodules, invasive procedures can be performed appropriately to clarify the nature of the lesion. The diagnosis cannot be made blindly to ensure that no incorrect diagnosis is made nor wrong treatment given.