MDS-065 Fatalities from Tumor Lysis Syndrome (TLS) After Anti-Hyperuricemic Monotherapy – Nationally Representative, Propensity Score Matched, Retrospective Study Comparison of Rasburicase and Allopurinol

• Published in: Clinical lymphoma, myeloma and leukemia Vol. 22; pp. S302 - S303
• Main Authors: Cairo, Mitchell, EdD, Jack R. Gallagher, Barnes, Yvonne, Drea, Edward, Carrol, Susan
• Format: Journal Article
• Language: English
• Published: Elsevier Inc 01.10.2022
• Subjects: anti-hyperuricemic; hyperuricemia; liquid tumor; MSD; observational; propensity score; propensity score matching; PSM; retrospective; TLS; tumor lysis syndrome; observational; PS; liquid tumor; retrospective; PSM; HU; anti-hyperuricemic; hyperuricemia; propensity score matching; tumor lysis syndrome; TLS; MSD; propensity score

Context: This is the first US-representative, retrospective, real-world propensity score (PS) matching study comparing the occurrence of TLS-associated fatalities following allopurinol monotherapy versus rasburicase monotherapy. We have previously found rasburicase significantly and more rapidly red...