2061 Acellular hyaluronic acid scaffold with growth factor delivery for cartilage repair in a large animal model

• Published in: Journal of clinical and translational science Vol. 2; no. S1; p. 3
• Main Authors: Martín, Anthony R., Patel, Jay M., Zlotnick, Hannah M., Sennet, Mackenzie L., Carey, James L., Mauck, Robert L.
• Format: Journal Article
• Language: English
• Published: Cambridge Cambridge University Press 01.06.2018
• Subjects: Basic/Translational Science/Team Science; Cartilage (articular); Cell adhesion; Chondrogenesis; Computed tomography; Defects; Growth factors; Hyaluronic acid; Knee; Mechanical properties; Polyethylene; Polyethylene oxide; Population studies; Subchondral bone; Surgery; Tissue engineering

OBJECTIVES/SPECIFIC AIMS: Focal cartilage injuries of the knee joint are common and present a treatment challenge due to minimal intrinsic repair. Cartilage tissue engineering techniques currently used in clinical practice are expensive, cumbersome, and often ineffective in patients with mechanical...